Department of Psychology, University of Denver, Denver, CO, USA.
Dev Psychobiol. 2021 Jul;63(5):985-996. doi: 10.1002/dev.22119. Epub 2021 Mar 21.
The objective of this review was to comprehensively evaluate the literature investigating associations between peripheral immune correlates and youth peer relationship dimensions. We aimed to identify potential aspects of peer relationships in childhood and adolescence that may be associated with immune profiles and to identify gaps in the field to provide suggestions for future research in this area. We conducted a systematic electronic search in health-related databases from the earliest records to December 2020. Search terms included domains related to youth, immune correlates, and peers. We summarized studies by the time between the peer measurement and the immune outcome. In the 17 included studies, associations between peer dimensions and immune outcomes varied substantially. Peer victimization in youth demonstrated the most consistent negative associations with immune health across development, including within 1 week of measurement, 1-3 years later, and 10 or more years later. This review indicated that that peer relationships during youth may have important associations with immune processes; however, there are several gaps in the literature regarding the operationalization of peer relationships, the timing of the immune measurement, and the type of immune outcome to be addressed by future research.
本次综述的目的在于全面评估外周免疫相关性与青少年同伴关系维度之间关系的文献。我们旨在确定儿童和青少年时期可能与免疫特征相关的潜在同伴关系方面，并确定该领域的空白，为该领域的未来研究提供建议。我们对健康相关数据库进行了系统的电子检索，检索时间从最早的记录到 2020 年 12 月。检索词包括与青年、免疫相关性和同伴相关的领域。我们根据同伴测量和免疫结果之间的时间来总结研究。在纳入的 17 项研究中，青少年时期的同伴维度与免疫结果之间的关联在整个发育过程中差异很大。青少年时期的同伴侵害与免疫健康之间表现出最一致的负相关，包括在测量后的 1 周内、1-3 年后和 10 年或更长时间后。本综述表明，青少年时期的同伴关系可能与免疫过程有重要关联；然而，文献中存在一些空白，涉及同伴关系的操作性定义、免疫测量的时间以及未来研究需要解决的免疫结果类型。
