Dalla Palma P, Dante S, Guazzieri S, Sperandio P
Institute of Pathological Anatomy, University of Padova, Italy.
Prostate. 1988;12(3):255-61. doi: 10.1002/pros.2990120308.
A 29-year-old man was admitted to the Department of Urology of the University of Padova with a diagnosis of prostatic adenocarcinoma. Cystourethrography showed a prostatic urethral obstruction, and CT scan demonstrated a low pelvic solid mass involving the prostate and the seminal vescicle. A radical prostatectomy was performed, and the prostate was found to be widely infiltrated by a neoplasia formed by tubules, papillary structures, and solid cords of cuboidal or flat elements, each having indistinct borders and scant cytoplasm, in a myxoid or fibrous stroma. "Schiller-Duval-like," PAS-diastase-resistant and alfa-fetoprotein hyaline bodies were present. An endodermal sinus (yolk-sac) tumor was diagnosed. There was infiltration of the periurethral prostatic ducts, prostatic urethra, and seminal vesicles and single lymph node metastasis. Testicular echotomography was negative. In spite of aggressive surgery and chemotherapy, the patient died 10 months after diagnosis. This is the third case in the literature after those presented by Benson and Michel.
一名29岁男性因前列腺腺癌诊断入住帕多瓦大学泌尿外科。膀胱尿道造影显示前列腺尿道梗阻，CT扫描显示盆腔下部实性肿块累及前列腺和精囊。进行了根治性前列腺切除术，发现前列腺被一种肿瘤广泛浸润，该肿瘤由小管、乳头状结构以及立方或扁平细胞组成的实性索条形成，在黏液样或纤维性基质中，每个结构边界不清且细胞质稀少。存在“席勒 - 杜瓦尔样”、耐PAS - 淀粉酶和甲胎蛋白透明小体。诊断为内胚窦（卵黄囊）瘤。有尿道周围前列腺导管、前列腺尿道和精囊浸润以及单个淋巴结转移。睾丸超声检查为阴性。尽管进行了积极的手术和化疗，患者在诊断后10个月死亡。这是继本森和米歇尔报道的病例之后文献中的第三例。
