Emergency and Critical Care Department, BluePearl Veterinary Specialists, New York, New York.
J Vet Emerg Crit Care (San Antonio). 2021 May;31(3):432-438. doi: 10.1111/vec.13033. Epub 2021 Mar 10.
To describe a case of the successful management of hypernatremia and multiple organ dysfunction syndrome secondary to joint supplement toxicity in a dog.
A 6-year-old neutered male Dachshund was presented for severe hypernatremia and neurological abnormalities after ingestion of a large quantity of joint supplements. The patient developed evidence of multiple organ dysfunction in the form of increased hepatocellular enzymes, prolongation of prothrombin and partial thromboplastin times, azotemia, and thrombocytopenia. Treatment was successful at correcting the hypernatremia and restoring neurological function, and organ dysfunction was successfully managed. Following multiple days of hospitalization and aggressive supportive care, the patient survived to discharge.
This case report describes the successful management and survival of multiple organ dysfunction associated with joint supplement toxicity. It also serves to highlight the potential for joint supplement overdose in veterinary patients, which is currently believed to be underrecognized.
描述一例犬因关节补充剂中毒而成功治疗高钠血症和多器官功能障碍综合征的病例。
一只 6 岁已绝育雄性达克斯猎犬因大量摄入关节补充剂后出现严重高钠血症和神经异常。该患者出现了多器官功能障碍的证据，包括肝酶升高、凝血酶原时间和部分凝血活酶时间延长、氮质血症和血小板减少症。治疗成功纠正了高钠血症并恢复了神经功能，成功治疗了器官功能障碍。经过多天的住院治疗和积极的支持性护理，该患者存活下来并出院。
本病例报告描述了成功管理和存活与关节补充剂毒性相关的多器官功能障碍。它还强调了关节补充剂过量在兽医患者中的潜在风险，目前认为这种情况被低估了。
