弱精子症和前列腺炎所致不育症患者的前列腺素水平

Prostaglandin levels in infertile patients affected by asthenozoospermia and prostatitis.

作者信息

Freixia R, Rosello J, Ramis I, Abian J, Bulbena O, Brassesco M, Gelpi E

机构信息

Department of Neurochemistry, Centro de Investigation y Desarrollo, Barcelona, Spain.

出版信息

Prostaglandins Leukot Essent Fatty Acids. 1988 Jan;31(1):41-4. doi: 10.1016/0952-3278(88)90163-9.

DOI:10.1016/0952-3278(88)90163-9

PMID:3375285

Abstract

19-hydroxy-prostaglandins and prostaglandins of the E series (19-OH PGEs) were estimated in the seminal plasma of asthenozoospermic patients (n = 15) and individuals affected by prostatitis (n = 10) and compared to controls (n = 13) and secretory azoospermic patients (n = 8). All of them were free from infections (except individuals affected by prostatitis), biochemical and ultrastructural problems. The results indicate that endogenous prostaglandin levels (19-OH PGEs and PGEs) bear no correlation either to motility or absence of spermatozoa. Significant increases of PGEs were observed in patients affected with prostatitis. Surprisingly PGE levels showed no correlation with the levels of 19-OH PGEs.

摘要

对弱精子症患者（n = 15）、前列腺炎患者（n = 10）的精浆中的19 - 羟基前列腺素和E系列前列腺素（19 - OH PGEs）进行了测定，并与对照组（n = 13）和分泌性无精子症患者（n = 8）进行比较。所有受试者均无感染（前列腺炎患者除外）、生化及超微结构问题。结果表明，内源性前列腺素水平（19 - OH PGEs和PGEs）与精子活力或精子缺失均无相关性。前列腺炎患者的PGEs水平显著升高。令人惊讶的是，PGE水平与19 - OH PGEs水平无相关性。