Postgraduate Program in Dentistry, Federal University of Paraíba, Campus I, João Pessoa, PB, 58051900, Brazil.
Postgraduate Program in Clinical Dentistry, State University of Campinas, Piracicaba, SP, Brazil.
Eur J Pediatr. 2021 Sep;180(9):2757-2764. doi: 10.1007/s00431-021-04024-z. Epub 2021 Mar 22.
The purpose of this study was to implement a model of permanent oral health care for oncopediatric patients and to observe its effects on severe oral mucositis and subsequent treatment interruptions. We performed a quasi-experimental study in the Pediatric Department of Napoleão Laureano Hospital, in the city of João Pessoa, Brazil. A integrated oral care was implemented by a dentistry team for prevention of comorbidities, such as infections, oral pain, oral function maintenance, oral mucositis, and interventions for lesions due to severe oral mucositis. The oral comorbidities were compared before and after the implementation. The duration of severe oral mucositis (SOM) before and after the interventions and the interruptions in treatment due to SOM were the main outcome measures. Permanent oral health care reduced the duration of SOM and reduced pediatric chemotherapy interruptions due to SOM by 81.8%.Conclusion: The permanent oral health care to offer to oncopediatric patients increased surveillance regarding oral comorbidities and reduced chemotherapy interruptions due to severe oral mucositis. This care plan could be adopted anywhere around the world. What is Known: • Several studies on oral care for pediatric oncology patients, especially regarding both prevention of and treatment for oral mucositis during antineoplastic therapy, have been published. What is New: • This study describes the benefits of permanent oral care with daily oral surveillance for pediatric patients, which reduced the duration of severe oral mucositis, increased surveillance and the efficiency in diagnostic for signs of oral mucositis, enabling early intervention, and decreased chemotherapy interruptions, contributing positively to the course of treatment.
本研究旨在为肿瘤儿科患者实施永久性口腔保健模式，并观察其对严重口腔黏膜炎及随后治疗中断的影响。我们在巴西若昂佩索阿市的纳波莱昂·劳雷亚诺医院儿科进行了一项准实验研究。一个牙科团队实施了综合口腔护理，以预防并发症，如感染、口腔疼痛、口腔功能维持、口腔黏膜炎以及严重口腔黏膜炎引起的病变干预。在实施前后比较了口腔并发症。主要观察指标为严重口腔黏膜炎（SOM）的持续时间、干预前后 SOM 以及因 SOM 导致的治疗中断。永久性口腔保健可缩短 SOM 的持续时间，并减少因 SOM 导致的儿科化疗中断 81.8%。结论：为肿瘤儿科患者提供的永久性口腔保健增加了对口腔并发症的监测，并减少了因严重口腔黏膜炎导致的化疗中断。该保健计划可在全球范围内采用。已知：• 已经发表了许多关于儿科肿瘤患者口腔护理的研究，特别是关于抗肿瘤治疗期间口腔黏膜炎的预防和治疗。新发现：• 本研究描述了对儿科患者进行日常口腔监测的永久性口腔护理的益处，可缩短严重口腔黏膜炎的持续时间，增加监测和口腔黏膜炎迹象的诊断效率，实现早期干预，并减少化疗中断，对治疗过程产生积极影响。
