Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Section, University of Naples Federico II, Naples.
Department of Urology, San Giovanni Hospital, Rome.
Arch Ital Urol Androl. 2021 Mar 18;93(1):42-47. doi: 10.4081/aiua.2021.1.42.
The aim of the study is to extrapolate clinical features of Premature Ejaculation (PE) patients and female partners of men affected with PE, in order to get a profile that can be of assistance for physicians within the dynamics of a couple, one of which is a PE patient. An observational, non-interventional, cross-sectional epidemiological study entitled IPER (Italian Premature Ejaculation Research) was conducted and included two different cohorts of subjects that were randomly sampled from a patient dataset of selected General Practitioners: 1. IPER-M sub-cohort (1.104 subjects) was made of male subjects in which they were then distinguished patients with or without PE based on the score of the PEDT questionnaire; IPER-F sub-cohort (1.109 subjects) was made of female subjects from an independent sample of women (therefore not the partners of the IPER-M males) in which they then distinguished those partners of a male subject with PE or not. In addition to an identical general questionnaire to explore demographic aspects and habits, each subcohort was then evaluated using validated questionnaires. No differences were noted between PE+/PE- patients in terms of alcohol consumption, smoking habits, physical activity nor stress condition in everyday life, employment, socio-economic class and marital status. While the prevalence of PE proportionally increased with age, excluding the 50-59 and 70-80 years decades, in the IPER-M group an overall statistically significant difference for the mean age between the PE+ and PE- groups (p = 0.002) was detected, but without reaching any difference amongst the different age classes in the IPER-F group. The PE+ patients reported a significantly lower frequency rate of sexual intercourse, worse QoL (p = 0.006 and p < 0.0001, respectively), and increased anxiety status (p < 0.0001 for both subgroups). This study shows that, rather than talking with a patient affected by PE it would be advisable to introduce the concept of couple counseling with the person patient and his partner, because it is only through classification of both partners as one couple and a full understanding of their mutual sexual experience that PE treatment can be optimized and its results measured accurately.
本研究旨在推断早泄 (PE) 患者及其受影响男性伴侣的临床特征，以便为夫妻关系中的医生提供帮助，因为其中一方是 PE 患者。进行了一项名为 IPER（意大利早泄研究）的观察性、非干预性、横断面流行病学研究，该研究纳入了两个不同的受试者队列，这些队列是从选定的全科医生的患者数据集中随机抽取的：1. IPER-M 子队列（1104 名受试者）由男性组成，根据 PEDT 问卷的评分，他们进一步分为有或没有 PE 的患者；IPER-F 子队列（1109 名受试者）由来自独立女性样本的女性组成（因此不是 IPER-M 男性的伴侣），他们进一步区分了有或没有 PE 男性伴侣的女性。除了一个相同的一般问卷来探索人口统计学和习惯方面外，每个子队列还使用经过验证的问卷进行了评估。PE+/PE-患者在饮酒、吸烟习惯、体育活动或日常生活中的压力状况、就业、社会经济阶层和婚姻状况方面没有差异。虽然 PE 的患病率随着年龄的增长而增加，但排除了 50-59 岁和 70-80 岁两个年龄段，在 IPER-M 组中，PE+和 PE-组之间的平均年龄存在总体统计学显著差异（p = 0.002），但在 IPER-F 组中，不同年龄组之间没有差异。PE+患者报告的性行为频率明显较低，生活质量较差（p = 0.006 和 p < 0.0001），焦虑状态增加（p < 0.0001 对于两个亚组）。这项研究表明，与其与受 PE 影响的患者交谈，不如向患者及其伴侣介绍夫妻咨询的概念，因为只有通过将双方归类为一对夫妻，并充分了解他们的相互性经验，才能优化 PE 治疗，并准确衡量其治疗结果。
