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确定创伤性损伤应激量表(TIDS)用于预测肌肉骨骼创伤后恢复率的临床有用临界值。

Identification of clinically-useful cut scores of the Traumatic Injuries Distress Scale (TIDS) for predicting rate of recovery following musculoskeletal trauma.

作者信息

Walton David M, Elliott James M, Lee Joshua, Fakhereddin Mohamad, Seo Wonjin

机构信息

School of Physical Therapy, Faculty of Health Sciences, Western University, London, Canada.

Northern Sydney Local Health District & Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.

出版信息

PLoS One. 2021 Mar 23;16(3):e0248745. doi: 10.1371/journal.pone.0248745. eCollection 2021.

Abstract

OBJECTIVE

The Traumatic Injuries Distress Scale (TIDS) is a 12-item self-report tool intended for prognostic risk phenotyping in people with acute musculoskeletal (MSK) trauma. The initial validation study showed good associations with outcomes 12 weeks later in a cohort of 72 acutely injured patients from one region in Canada. This study aims to provide further clinical utility through identification of meaningful cut scores in a larger, mixed geography sample, and expands the prediction window from 12 to 52 weeks.

METHODS

Data were drawn from databanks in London, Canada and Chicago, United States. Participants were recruited within 3 weeks of non-catastrophic MSK trauma and followed for 12 months. Using outcomes trajectories, the TIDS underwent linear regression-based analysis to predict 52-week outcomes, and area under the receiver operating characteristic curves to identify discriminative accuracy and meaningful cut scores.

RESULTS

N = 224 participants with acute trauma were followed and both %Interference and Pain Severity were captured at intake and 3 follow-ups to establish curvilinear recovery trajectories. The TIDS explained significant variance in both the interference and severity outcomes after controlling for sex, region of injury, and baseline scores. ROC analysis revealed significant discriminative accuracy for predicting both the trajectories and the distal outcomes over 52 weeks. The TIDS was more accurate for identifying the low-risk than high-risk patients.

CONCLUSION

The TIDS is a useful tool for 'ruling out' high risk of poor outcome in a mixed sample of participants from two different countries.

IMPACT STATEMENT

The TIDS will be a useful tool for clinicians to predict the rate of recovery by displaying meaningful cut-scores for their patients after an acute musculoskeletal injury. This could lead to reduced burden of care for low risk patients and more informed treatment options for higher risk patients.

摘要

目的

创伤损伤困扰量表(TIDS)是一种包含12个条目的自我报告工具,旨在对急性肌肉骨骼(MSK)创伤患者进行预后风险表型分析。最初的验证研究表明,在加拿大一个地区的72名急性受伤患者队列中,该量表与12周后的结果有良好的相关性。本研究旨在通过在更大的、地域混合的样本中确定有意义的临界值,进一步提高该量表的临床实用性,并将预测窗口从12周扩大到52周。

方法

数据来自加拿大伦敦和美国芝加哥的数据库。参与者在非灾难性MSK创伤后3周内招募,并随访12个月。利用结果轨迹,对TIDS进行基于线性回归的分析以预测52周后的结果,并通过受试者工作特征曲线下面积来确定判别准确性和有意义的临界值。

结果

对224名急性创伤参与者进行了随访,并在入组时和3次随访中记录了干扰百分比和疼痛严重程度,以建立曲线恢复轨迹。在控制了性别、损伤部位和基线分数后,TIDS在干扰和严重程度结果方面均解释了显著的方差。ROC分析显示,在预测52周内的轨迹和远端结果方面具有显著的判别准确性。TIDS在识别低风险患者方面比高风险患者更准确。

结论

TIDS是一种有用的工具,可用于“排除”来自两个不同国家的混合样本参与者中不良结局的高风险。

影响声明

TIDS将成为临床医生的有用工具,通过为急性肌肉骨骼损伤后的患者显示有意义的临界值来预测恢复率。这可能会减轻低风险患者的护理负担,并为高风险患者提供更明智的治疗选择。

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