Shaw M P, Wallace W H, Eden O B
Department of Paediatric Oncology, Royal Hospital for Sick Children, Edinburgh, Scotland.
Pediatr Hematol Oncol. 1997 Jan-Feb;14(1):79-83. doi: 10.3109/08880019709030888.
A 25-year-old male previously treated (age 9 years) for acute lymphoblastic leukemia developed a spindle cell carcinoma of the tongue. Possible causes for the development of his second malignancy are discussed. A combination of scatter from cranial irradiation, poor oral hygiene, alcohol consumption, and cigarette smoking is likely to be contributory. Genetic predisposition can never be fully excluded.
一名25岁男性曾在9岁时接受过急性淋巴细胞白血病治疗，之后患上了舌部梭形细胞癌。文中讨论了其发生第二种恶性肿瘤的可能原因。头部放疗散射、口腔卫生差、饮酒和吸烟等因素综合起来可能起到了促成作用。遗传易感性也永远无法完全排除。
