Hafeman D G, Parce J W, McConnell H M
Molecular Devices Corporation, Palo Alto, CA 94304.
Science. 1988 May 27;240(4856):1182-5. doi: 10.1126/science.3375810.
Numerous biochemical reactions can be measured potentiometrically through changes in pH, redox potential, or transmembrane potential. An alternating photocurrent through an electrolyte-insulator-semiconductor interface provides a highly sensitive means to measure such potential changes. A spatially selectable photoresponse permits the determination of a multiplicity of chemical events with a single semiconductor device.
许多生化反应可以通过pH值、氧化还原电位或跨膜电位的变化进行电位测量。通过电解质-绝缘体-半导体界面的交变光电流提供了一种测量此类电位变化的高度灵敏的方法。空间可选择的光响应允许用单个半导体器件测定多种化学事件。
