单细胞测序，肺癌研究中的一项先进技术。
Single-Cell Sequencing, an Advanced Technology in Lung Cancer Research.
作者信息
Wang Hao, Meng Die, Guo Haoyue, Sun Chenglong, Chen Peixin, Jiang Minlin, Xu Yi, Yu Jia, Fang Qiyu, Zhu Jun, Zhao Wencheng, Wu Shengyu, Zhao Sha, Li Wei, Chen Bin, Wang Lei, He Yayi
机构信息
Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, People's Republic of China.
Tongji University, School of Medicine, Shanghai, 200433, People's Republic of China.
出版信息
Onco Targets Ther. 2021 Mar 16;14:1895-1909. doi: 10.2147/OTT.S295102. eCollection 2021.
Single-cell sequencing (SCS) which has an unprecedentedly high resolution is an advanced technique for cancer research. Lung cancer still has a high mortality and morbidity. For further understanding the lung cancer, SCS is also been applied to lung cancer research to investigate its heterogeneity, metastasis, drug resistance, tumor microenvironment and many other issues. In this review, we summarized lung cancer research using SCS and their research achievements.
单细胞测序（SCS）具有前所未有的高分辨率，是癌症研究的一项先进技术。肺癌的死亡率和发病率仍然很高。为了进一步了解肺癌，SCS也被应用于肺癌研究，以探讨其异质性、转移、耐药性、肿瘤微环境等诸多问题。在这篇综述中，我们总结了使用SCS进行的肺癌研究及其研究成果。
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