Wagnew Yohannes, Hagos Tsega, Weldegerima Berhanemeskel, Debie Ayal
University of Gondar Comprehensive and Specialized Referral Hospital, University of Gondar, Gondar, Ethiopia.
Department of Health Systems and Policy, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Clinicoecon Outcomes Res. 2021 Mar 15;13:165-174. doi: 10.2147/CEOR.S299050. eCollection 2021.
Malaria, a protozoan disease caused by the genus , is responsible for serious illnesses and death across the world. RTS, S/AS01 (Mosquirix™) is a recombinant protein-based malaria vaccine valuable for the prevention and control of the disease. However, studies done so far on the willingness to pay (WTP) malaria vaccine have been inadequate to inform policy-makers.
A community-based cross-sectional study was conducted to assess the WTP for childhood malaria vaccine and associated factors among caregivers of under-five children from February to April 2019 in West Dembia district. A multistage stratified systematic sampling technique was used, and the contingent valuation method was used to estimate caregivers' willingness to pay for the vaccine. AOR with 95% CI and less than 0.05 p-values were used to declare factors associated with WTP.
Overall, 60.6% (95% CI: 56.60, 64.40%) of caregivers of under-five children were WTP for the childhood malaria vaccine at a price of US$ 23.11 per full doses. Urban residence (AOR=1.78, 95% CI: 1.04, 3.04), educational status (AOR=3.27; 95% CI: 1.07, 9.94) and vaccination experience for children (AOR= 2.12; 95% CI: 1.29, 3.48) were positively associated with the WTP. WTP for the vaccine was higher among rich households (AOR=3.15; 95% CI: 1.90, 5.22), caregivers who had the previous history of malaria attack (AOR=2.62; 95% CI: 1.68, 4.08), households with fewer members (AOR=1.59; 95% CI: 1.06, 2.40), and families more knowledgeable about malaria prevention and control (AOR=3.56; 95% CI: 1.83, 6.93) compared with their counterparts.
The majority of the participants were WTP for the childhood malaria vaccine. A significant rise in willingness to purchase was observed at price below the profile price. Thus, it is of great value to policy-makers to understand the price sensitivity before setting the price of the vaccine.
疟疾是由疟原虫属引起的原生动物疾病,在全球范围内导致严重疾病和死亡。RTS,S/AS01(Mosquirix™)是一种基于重组蛋白的疟疾疫苗,对预防和控制该疾病具有重要价值。然而,迄今为止关于疟疾疫苗支付意愿(WTP)的研究还不足以供政策制定者参考。
2019年2月至4月在西登比亚地区进行了一项基于社区的横断面研究,以评估五岁以下儿童看护者对儿童疟疾疫苗的支付意愿及相关因素。采用多阶段分层系统抽样技术,并使用条件估值法来估计看护者为疫苗支付的意愿。使用95%置信区间的调整后比值比(AOR)和小于0.05的p值来确定与支付意愿相关的因素。
总体而言,五岁以下儿童的看护者中有60.6%(95%置信区间:56.60,64.40%)愿意以每剂23.11美元的价格为儿童疟疾疫苗付费。城市居住(AOR=1.78,95%置信区间:1.04,3.04)、教育程度(AOR=3.27;95%置信区间:1.07,9.94)和儿童的疫苗接种经历(AOR=2.12;95%置信区间:1.29,3.48)与支付意愿呈正相关。富裕家庭(AOR=3.15;95%置信区间:1.90,5.22)、有疟疾发作既往史的看护者(AOR=2.62;95%置信区间:1.68,4.08)、成员较少的家庭(AOR=1.59;95%置信区间:1.06,2.40)以及对疟疾预防和控制了解较多的家庭(AOR=3.56;95%置信区间:1.83,6.93)的疫苗支付意愿高于其对应家庭。
大多数参与者愿意为儿童疟疾疫苗付费。在低于预期价格时观察到购买意愿显著上升。因此,政策制定者在设定疫苗价格之前了解价格敏感性具有重要价值。