Assakran Bandar Saad, Alrakbi Khaled, Alharbi Meshari A, Almatroudi Moath A, Alshowaiman Asim, Alromaih Abdullah Homood, Alaqil Naif, Alharbi Basil, Alsoghayer Ali
General Surgery, King Fahad Specialist Hospital, Buraydah, SAU.
General Surgery, King Fahad Specialist Hospital, Burydah, SAU.
Cureus. 2021 Feb 17;13(2):e13396. doi: 10.7759/cureus.13396.
Introduction In obese patients, hiatal hernia (HH) can be asymptomatic or may present with one or few symptoms, such as heartburn, nausea, or vomiting. Routine upper gastrointestinal (GI) endoscopy is the most frequent method used to determine the presence of any abnormalities, including HH. This study aimed to assess the prevalence of asymptomatic HH in obese patients during routine upper GI endoscopy assessments and to examine the correlation with body mass index (BMI). Materials and methods This was an observational, retrospective cohort study conducted at King Fahad Specialist Hospital, Buraydah, Qassim, Saudi Arabia. The data were extracted from the medical records and electronic charts of all obese patients who underwent preoperative upper GI endoscopy assessment between January 2017 and December 2019. Data were tabulated in Microsoft Excel and analyzed using the Statistical Package for the Social Sciences (SPSS) Version 21 (IBM Corp., Armonk, NY, USA). Results Among the 690 obese patients, HH was found in 103 (14.9%) patients. The chi-square test revealed that abdominal pain (X=3.885; p=0.049), shortness of breath (X=8.057; p=0.005), vomiting (X=4.302; p=0.038), nausea (X=4.090; p=0.043), and other HH symptoms (X=3.897, p=0.048) were the most frequently reported HH related symptoms, but BMI was not (X=2.126; p=0.345). In the multivariate regression model, the use of PPI (proton-pump inhibitor) medication (adjusted OR [AOR]=0.237; 95% CI=0.074-0.760; p=0.023) was found to be higher in those with HH. Vomiting (AOR=1.722; 95% CI=1.025-2.890; p=0.040) and nausea (AOR=1.698; 95% CI=1.012-2.849; p=0.045) were the most frequently reported symptoms related to HH. Conclusion Asymptomatic HH among obese patients is not widely prevalent in our region. The use of PPI medications was found to decrease the symptoms associated with HH, such as vomiting and nausea. However, there was no evidence linking BMI to the development of HH.
引言 在肥胖患者中,食管裂孔疝(HH)可能无症状,也可能表现出一种或几种症状,如烧心、恶心或呕吐。常规上消化道(GI)内镜检查是用于确定包括HH在内的任何异常情况的最常用方法。本研究旨在评估肥胖患者在常规上消化道内镜检查评估中无症状HH的患病率,并研究其与体重指数(BMI)的相关性。
材料与方法 这是一项在沙特阿拉伯卡西姆布赖代的法赫德国王专科医院进行的观察性回顾性队列研究。数据从2017年1月至2019年12月期间接受术前上消化道内镜检查评估的所有肥胖患者的病历和电子病历中提取。数据录入Microsoft Excel表格,并使用社会科学统计软件包(SPSS)21版(美国纽约州阿蒙克市IBM公司)进行分析。
结果 在690例肥胖患者中,103例(14.9%)发现有HH。卡方检验显示,腹痛(X=3.885;p=0.049)、呼吸急促(X=8.057;p=0.005)、呕吐(X=4.302;p=0.038)、恶心(X=4.090;p=0.043)以及其他HH相关症状(X=3.897,p=0.048)是最常报告的HH相关症状,但BMI不是(X=2.126;p=0.345)。在多变量回归模型中,发现使用质子泵抑制剂(PPI)药物(调整后比值比[AOR]=0.237;95%置信区间=0.074-0.760;p=0.023)在HH患者中更高。呕吐(AOR=1.722;95%置信区间=1.025-2.890;p=0.040)和恶心(AOR=1.698;95%置信区间=1.012-2.849;p=0.045)是最常报告的与HH相关的症状。
结论 在我们地区,肥胖患者中的无症状HH并不普遍。发现使用PPI药物可减轻与HH相关的症状,如呕吐和恶心。然而,没有证据表明BMI与HH的发生有关。