Yang Xianxian, Tang Wenge, Mao Deqiang, Shu Qiang, Yin Hong, Tang Cheng, Zhang Ming, Li Can, Ding Xianbin
Chongqing Center for Disease Control and Prevention, Chongqing, 400042, China.
Rong Chang District Center for Disease Control and Prevention, Chongqing, 402473, China.
Arch Osteoporos. 2021 Mar 23;16(1):57. doi: 10.1007/s11657-021-00910-z.
Standardized prevalence of osteoporosis was 19.90% in the whole subjects aged between 50 and 87, 5.87% in men and 30.23% in women respectively. Risk factors associated with osteoporosis were analyzed. It is the first time to estimate the prevalence and characterize the epidemiology of osteoporosis in Chongqing, China.
To investigate bone mineral density (BMD) profiles, osteoporosis prevalence, and its risk factors among residents aged above 20 years old in Chongqing Municipality, China.
The study population consisted of 770 men and 1085 women aged 20 years and older with BMD measurements using central dual-energy X-ray absorptiometry (DXA). Information on sociodemographic characteristics and the potential risk factors associated with osteoporosis were collected by a standardized interviewer-administered questionnaire.
Crude prevalence of osteoporosis was 12.99% in the whole subjects, 4.42% for men, and 19.08% for women by WHO criteria at various skeletal regions (among lumbar spine, femoral neck, and total hip). Standardized prevalence of osteoporosis was 19.90% in the whole subjects aged between 50 and 87, 5.87% in men and 30.23% in women respectively. Prevalence of osteoporosis increased with age, and the prevalence of osteoporosis in women was 6.10 times higher than it in men. The prevalence of osteoporosis was significantly associated with the past medical history of fracture (OR = 1.794, P = 0.007); overweight and obesity were considered to be protective factors for osteoporosis with OR of 0.514 and 0.300, respectively; high school graduate (OR = 0.399, P = 0.000 ) and milk intake (OR = 0.648, P = 0.008) were also protective factors for osteoporosis in men and women considered together; menopause was an independent risk factor of osteoporosis in females (OR = 1.782, P = 0.029); current smoking was an independent risk factor of osteoporosis in males (OR = 2.437, P = 0.046).
The prevalence of osteoporosis and osteopenia was high among residents in Chongqing, China. Health education and behavior intervention should be focused on the elderly or female residents to promote the formulation of healthy lifestyle. Necessary steps are needed for more public education and a wider dissemination of information about osteoporosis and its prevention.
在年龄介于50至87岁的所有受试者中，骨质疏松症的标准化患病率为19.90%，男性为5.87%，女性为30.23%。对与骨质疏松症相关的风险因素进行了分析。这是首次在中国重庆估算骨质疏松症的患病率并描述其流行病学特征。
调查中国重庆市20岁及以上居民的骨密度（BMD）情况、骨质疏松症患病率及其风险因素。
研究人群包括770名男性和1085名20岁及以上的女性，使用中央双能X线吸收法（DXA）测量骨密度。通过标准化的访谈问卷收集社会人口学特征信息以及与骨质疏松症相关的潜在风险因素。
按照世界卫生组织标准，在各个骨骼部位（腰椎、股骨颈和全髋部），所有受试者中骨质疏松症的粗患病率为12.99%，男性为4.42%，女性为19.08%。年龄介于50至87岁的所有受试者中，骨质疏松症的标准化患病率为19.90%，男性为5.87%，女性为30.23%。骨质疏松症患病率随年龄增长而升高，女性骨质疏松症患病率比男性高6.10倍。骨质疏松症患病率与既往骨折病史显著相关（OR = 1.794，P = 0.007）；超重和肥胖被认为是骨质疏松症的保护因素，OR分别为0.514和0.300；高中文化程度（OR = 0.399，P = 0.000）和牛奶摄入量（OR = 0.648，P = 0.008）在综合考虑男性和女性时也是骨质疏松症的保护因素；绝经是女性骨质疏松症的独立危险因素（OR = 1.782，P = 0.029）；当前吸烟是男性骨质疏松症的独立危险因素（OR = 2.437，P = 0.046）。
中国重庆居民中骨质疏松症和骨质减少症的患病率较高。健康教育和行为干预应聚焦于老年或女性居民，以促进健康生活方式的形成。需要采取必要措施进行更多的公众教育，并更广泛地传播有关骨质疏松症及其预防的信息。
