Department of Orthopaedics, Wuhan Hospital of Traditional Chinese and Western Medicine, Wuhan, 430022, China.
Department of Occupational and Environmental Health, School of Public Health, Wuhan University, Wuhan, 430071, China.
Arch Osteoporos. 2023 Apr 15;18(1):49. doi: 10.1007/s11657-023-01245-7.
It is the first time to estimate the prevalence and characterize of osteoporosis in Hubei province, China. The prevalence of osteoporosis was 12.19%, 3.69% for males, and 18.94% for females; 56.6% were diagnosed with osteopenia, 44.96% for males, and 65.84% for females.
The disease burden of osteoporosis is increasing, but there are few studies on the prevalence and risk factors in Hubei, China. This study aims to analyze the prevalence of osteoporosis using dual-energy X-ray absorptiometry (DXA) measurement and the risk factors of osteoporosis using epidemiological survey methods.
To explore the prevalence of osteoporosis and osteopenia in Hubei province, and provide the epidemiological basis for policymakers, to reduce the prevalence of osteoporosis METHODS: Based on data derived from the epidemiological survey of osteoporosis in Hubei province in 2018, 1592 residents aged 40 and above from 32 neighborhood committees/villages in 4 districts/counties of Hubei province were selected by multistage stratified random sampling. The lumbar spine AP (L1-L4 and L2-L4), femoral neck, and total hip BMD were measured using DXA of the internationally recognized gold standard and assessed according to WHO diagnostic criteria, utilizing unconditional logistic regression to explore the risk factors of osteoporosis and osteopenia.
The overall crude prevalence of osteoporosis was 12.19%, 3.69% for males, and 18.94% for females. Osteopenia was diagnosed in 56.6% of all participants, 44.96% in males, and 65.84% in females. Increasing age, females, and underweight were related to the high prevalence of osteoporosis and osteopenia, while people with higher levels of education, overweight, and obese had a low prevalence of osteoporosis and osteopenia. In women, the absence of chronic disease and moderate intake of dairy products probably be associated with the low prevalence of osteopenia.
The prevalence of osteoporosis and osteopenia is high in Hubei, China. The risk of prevalence of osteoporosis and osteopenia was higher in females and people with higher age and low BMI. While high BMI, high education, the absence of chronic disease, and intaking dairy moderately were negatively correlated with the prevalence of osteopenia or osteoporosis. The government should support the prevention and treatment of osteoporosis.
分析湖北省骨质疏松症的患病率和骨质疏松症及低骨量的危险因素，为决策者提供骨质疏松症的流行病学依据，以降低骨质疏松症的患病率。
基于 2018 年湖北省骨质疏松症流行病学调查数据，采用多阶段分层随机抽样方法，选取湖北省 4 个区/县 32 个居委会/村的 1592 名 40 岁及以上居民，采用国际公认的金标准双能 X 线吸收法（DXA）测量腰椎（L1-L4 和 L2-L4）、股骨颈和全髋 BMD，并根据世界卫生组织（WHO）诊断标准进行评估，采用非条件 logistic 回归分析骨质疏松症和低骨量的危险因素。
总体粗患病率为 12.19%，男性为 3.69%，女性为 18.94%。所有参与者中，56.6%被诊断为骨质疏松症，男性为 44.96%，女性为 65.84%。年龄较大、女性和体重不足与骨质疏松症和低骨量的高患病率相关，而教育程度较高、超重和肥胖的人群骨质疏松症和低骨量的患病率较低。在女性中，无慢性病和适度摄入乳制品可能与低骨量的低患病率有关。
中国湖北省骨质疏松症和低骨量的患病率较高。女性和年龄较大、BMI 较低的人群患骨质疏松症和低骨量的风险较高。而较高的 BMI、较高的教育程度、无慢性病和适度摄入乳制品与低骨量或骨质疏松症的患病率呈负相关。政府应支持骨质疏松症的预防和治疗。
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