Faber L P
Department of Cardiovascular-Thoracic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois.
Surg Clin North Am. 1988 Jun;68(3):525-43. doi: 10.1016/s0039-6109(16)44532-9.
Thoracic surgeons are asked to evaluate various diseases related to asbestos, including benign pleural plaques, malignant mesothelioma, and lung cancer. The benign localized mesothelioma is usually considered in the differential diagnosis of pleural tumors, but it is not related to asbestos exposure. Benign pleural plaques can be diagnosed by history and radiologic studies, and surgery offers no therapeutic benefit. Diffuse malignant mesothelioma is currently an incurable tumor, but pleurectomy can afford some palliation. Extrapleural pneumonectomy can be accomplished with an acceptable mortality, but long-term results do not justify its routine use. Lung cancer in those exposed to asbestos fibers is treated no differently than when it occurs in the general population.
胸外科医生被要求评估各种与石棉相关的疾病,包括良性胸膜斑、恶性间皮瘤和肺癌。良性局限性间皮瘤通常在胸膜肿瘤的鉴别诊断中予以考虑,但它与石棉暴露无关。良性胸膜斑可通过病史和影像学检查进行诊断,手术并无治疗益处。弥漫性恶性间皮瘤目前是一种无法治愈的肿瘤,但胸膜切除术可提供一定程度的缓解。胸膜外全肺切除术可在可接受的死亡率下完成,但长期效果并不支持其常规使用。接触石棉纤维者患肺癌的治疗方法与普通人群患肺癌的治疗方法并无不同。