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Statins and Atherosclerotic Lesion Microcalcification: A New Mechanism for Plaque Stability?

作者信息

Doran Amanda C, Terry James G, Carr John Jeffrey, Linton MacRae F

机构信息

Division of Cardiovascular Medicine, Department of Medicine (A.C.D., J.J.C., M.F.L.), Vanderbilt University Medical Center, Nashville, TN.

Vanderbilt Institute for Infection, Immunology, and Inflammation (A.C.D.), Vanderbilt University Medical Center, Nashville, TN.

出版信息

Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1306-1308. doi: 10.1161/ATVBAHA.121.315949. Epub 2021 Mar 24.

DOI:10.1161/ATVBAHA.121.315949
PMID:33760629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8011331/
Abstract
摘要

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本文引用的文献

1
Innate and adaptive immunity in cardiovascular calcification.先天性和适应性免疫在心血管钙化中的作用。
Atherosclerosis. 2020 Aug;306:59-67. doi: 10.1016/j.atherosclerosis.2020.02.016. Epub 2020 Feb 28.
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Pravastatin polarizes the phenotype of macrophages toward M2 and elevates serum cholesterol levels in apolipoprotein E knockout mice.普伐他汀可使巨噬细胞表型向M2极化，并升高载脂蛋白E基因敲除小鼠的血清胆固醇水平。
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Effects of Statins on Coronary Atherosclerotic Plaques: The PARADIGM Study.他汀类药物对冠状动脉粥样硬化斑块的影响：PARADIGM 研究。
JACC Cardiovasc Imaging. 2018 Oct;11(10):1475-1484. doi: 10.1016/j.jcmg.2018.04.015. Epub 2018 Jun 13.
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Coronary Artery Calcification and its Progression: What Does it Really Mean?冠状动脉钙化及其进展：它到底意味着什么？
JACC Cardiovasc Imaging. 2018 Jan;11(1):127-142. doi: 10.1016/j.jcmg.2017.10.012.
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Association of Coronary Artery Calcium in Adults Aged 32 to 46 Years With Incident Coronary Heart Disease and Death.32 至 46 岁成年人的冠状动脉钙与冠心病事件和死亡的关系。
JAMA Cardiol. 2017 Apr 1;2(4):391-399. doi: 10.1001/jamacardio.2016.5493.
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Intra-Section Analysis of Human Coronary Arteries Reveals a Potential Role for Micro-Calcifications in Macrophage Recruitment in the Early Stage of Atherosclerosis.人类冠状动脉的节段内分析揭示了微钙化在动脉粥样硬化早期巨噬细胞募集过程中的潜在作用。
PLoS One. 2015 Nov 10;10(11):e0142335. doi: 10.1371/journal.pone.0142335. eCollection 2015.
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Has our understanding of calcification in human coronary atherosclerosis progressed?我们对人冠状动脉粥样硬化中的钙化的理解是否有所进展？
Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):724-36. doi: 10.1161/ATVBAHA.113.302642. Epub 2014 Feb 20.
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Calcium density of coronary artery plaque and risk of incident cardiovascular events.冠状动脉斑块钙密度与心血管事件发生风险。
JAMA. 2014 Jan 15;311(3):271-8. doi: 10.1001/jama.2013.282535.
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Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk individuals.新型风险标志物在改善中危人群心血管风险评估中的比较。
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Coronary artery calcium progression: an important clinical measurement? A review of published reports.冠状动脉钙进展：重要的临床测量指标？对已发表报告的综述。
J Am Coll Cardiol. 2010 Nov 9;56(20):1613-22. doi: 10.1016/j.jacc.2010.06.038.