Farooq Tahir, Adeel Muhammad, He Zifu, Umar Muhammad, Shakoor Noman, da Silva Washington, Elmer Wade, White Jason C, Rui Yukui
Beijing Key Laboratory of Farmland Soil Pollution Prevention and Remediation and College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, P.R. China.
Plant Protection Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, P.R. China.
ACS Nano. 2021 Apr 27;15(4):6030-6037. doi: 10.1021/acsnano.0c10910. Epub 2021 Mar 24.
Phytoviruses are highly destructive plant pathogens, causing significant agricultural losses due to their genomic diversity, rapid, and dynamic evolution, and the general inadequacy of management options. Although an increasing number of studies are being published demonstrating the efficacy of engineered nanomaterials to treat a range of plant pathogens, very little work has been done with phytoviruses. Herein, we describe the emerging field of "Nanophytovirology" as a potential management approach to combat plant viral diseases. Because of their special physiochemical properties, nanoparticles (NPs) can interact with viruses, their vectors, and the host plants in a variety of specific and useful ways. We specifically describe the potential mechanisms underlying NPs-plant-virus interactions and explore the antiviral role of NPs. We discuss the limited literature, as well as the challenges and research gaps that are instrumental to the successful development of a nanotechnology-based, multidisciplinary approach for timely detection, treatment, and prevention of viral diseases.
植物病毒是极具破坏性的植物病原体，由于其基因组多样性、快速且动态的进化以及管理手段普遍不足，导致了重大的农业损失。尽管越来越多的研究表明工程纳米材料对一系列植物病原体具有治疗效果，但针对植物病毒的研究却很少。在此，我们将“纳米植物病毒学”这一新兴领域描述为一种对抗植物病毒病的潜在管理方法。由于其特殊的物理化学性质，纳米颗粒（NPs）可以通过多种特定且有用的方式与病毒、其传播媒介以及宿主植物相互作用。我们具体描述了NPs-植物-病毒相互作用的潜在机制，并探讨了NPs的抗病毒作用。我们讨论了有限的文献，以及对基于纳米技术的多学科方法成功用于及时检测、治疗和预防病毒病至关重要的挑战和研究空白。
