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药物性颈部肌张力障碍所致慢性寰枢椎旋转固定的自然史、神经影像学检查及治疗选择

Natural History, Neuroradiological Workup, and Management Options of Chronic Atlantoaxial Rotatory Fixation Caused by Drug-Induced Cervical Dystonia.

作者信息

Ishikawa Yuki, Kato So, Ganau Mario, Hirai Shima, Oshima Yasushi, Tanaka Sakae

机构信息

Department of Orthopaedic Surgery, The University of Tokyo, 113-8655, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan.

Department of Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

出版信息

Case Rep Orthop. 2021 Mar 3;2021:6683268. doi: 10.1155/2021/6683268. eCollection 2021.

Abstract

Atlantoaxial rotatory fixation (AARF) resulting from drug-induced cervical dystonia (DICD) represents an extremely rare complication of antipsychotic treatment, requiring a comprehensive assessment of pharmacologic therapy and timely radiologic workup. We report a chronic case of Fielding type I, Pang type I AARF secondary to schizophrenia treatment in a 16-year-old girl, along with a review of the literature on the management challenges posed in this condition. In this scenario, torticollis may just represent the tip of the iceberg, and only an effective multidisciplinary approach increases the chances of satisfactory correction with closed reduction, hence avoiding the burden of more invasive treatment options.

摘要

药物性颈部肌张力障碍(DICD)导致的寰枢椎旋转固定(AARF)是抗精神病药物治疗极为罕见的并发症,需要对药物治疗进行全面评估并及时进行影像学检查。我们报告了一名16岁女孩因精神分裂症治疗继发的Fielding I型、Pang I型慢性AARF病例,并对该病治疗挑战的相关文献进行综述。在这种情况下,斜颈可能只是冰山一角,只有有效的多学科方法才能增加闭合复位满意矫正的机会,从而避免更具侵入性治疗选择带来的负担。

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