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膀胱炎性肌纤维母细胞瘤的保守治疗方法:一例病例报告及文献综述

A Conservative Approach to Inflammatory Myofibroblastic Tumor of the Bladder: A Case Report and Review of Literature.

作者信息

Abou Zahr Rawad, Ghabi Elie, Idrissi-Kaitouni Mehdi, Roumeguere Thierry

机构信息

Urology Department, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.

Urology Department, Saint George Hospital University Medical Center, University of Balamand, Beirut, Lebanon.

出版信息

Case Rep Urol. 2021 Mar 8;2021:6660356. doi: 10.1155/2021/6660356. eCollection 2021.

DOI:10.1155/2021/6660356
PMID:33763285
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7964097/
Abstract

Inflammatory myofibroblastic tumors (IMTs) are particularly rare tumors that have been described in various anatomic locations, of which the urinary bladder is the most common. These benign tumors are amendable to conservative therapy but are notoriously difficult to diagnose given their mimicry of malignant sarcomas and sarcomatoid carcinomas, making an accurate diagnosis paramount to spare a patient radical and unnecessary treatment. We hereby present the case of a 37-year-old female patient who was diagnosed with an IMT of the urinary bladder during workup for painless gross hematuria. Patient was successfully managed with a laparoscopic partial cystectomy and is free of recurrence 5 years after surgery. IMTs are rare benign tumors that share the same clinical presentation as malignant bladder tumors. Deep biopsy and experienced pathologist are crucial in establishing diagnosis and avoiding patient radical treatment. This case is a classical demonstration of a remarkably rare tumor that was adequately managed with conservative therapy, achieving excellent clinical outcomes.

摘要

炎性肌纤维母细胞瘤(IMTs)是一种极为罕见的肿瘤,已在各种解剖部位被描述,其中膀胱是最常见的部位。这些良性肿瘤适合保守治疗,但鉴于它们易与恶性肉瘤和肉瘤样癌相混淆,诊断 notoriously 困难,因此准确诊断对于避免患者接受根治性和不必要的治疗至关重要。我们在此报告一例37岁女性患者,她在因无痛性肉眼血尿进行检查时被诊断为膀胱IMT。患者通过腹腔镜部分膀胱切除术成功治疗,术后5年无复发。IMTs是罕见的良性肿瘤,与恶性膀胱肿瘤具有相同的临床表现。深度活检和经验丰富的病理学家对于确立诊断和避免患者接受根治性治疗至关重要。本病例是一个典型的例子,展示了一种极为罕见的肿瘤通过保守治疗得到充分管理,并取得了优异的临床结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e7/7964097/32ae41c57b16/CRIU2021-6660356.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e7/7964097/c87232e7dd19/CRIU2021-6660356.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e7/7964097/ee9c8f38cd96/CRIU2021-6660356.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e7/7964097/32ae41c57b16/CRIU2021-6660356.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e7/7964097/c87232e7dd19/CRIU2021-6660356.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e7/7964097/ee9c8f38cd96/CRIU2021-6660356.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e7/7964097/32ae41c57b16/CRIU2021-6660356.003.jpg

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Urol Case Rep. 2020 Oct 29;34:101474. doi: 10.1016/j.eucr.2020.101474. eCollection 2021 Jan.
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A Rare Case of Inflammatory Myofibroblastic Tumor of the Prostate and Review of the Literature.前列腺炎性肌纤维母细胞瘤 1 例报告并文献复习
In Vivo. 2020 Jul-Aug;34(4):2043-2048. doi: 10.21873/invivo.12005.
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Prolapsing inflammatory myofibroblastic tumor of the urinary bladder: A case report and a review of literature.
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Urol Case Rep. 2020 Apr 4;31:101191. doi: 10.1016/j.eucr.2020.101191. eCollection 2020 Jul.
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Pseudosarcomatous myofibroblastic proliferation of the urinary bladder: a rare entity.膀胱假肉瘤性肌纤维母细胞增生:一种罕见病变。
Urology. 2014 Jun;83(6):1409-11. doi: 10.1016/j.urology.2014.03.004. Epub 2014 Apr 24.
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Inflammatory myofibroblastic tumors of the genitourinary tract--single entity or continuum?泌尿生殖道炎性肌纤维母细胞瘤——单一实体还是连续体?
J Urol. 2008 Oct;180(4):1235-40. doi: 10.1016/j.juro.2008.06.049. Epub 2008 Aug 15.
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Pseudosarcomatous myofibroblastic lesion of the urinary bladder: a rare entity posing a diagnostic challenge and therapeutic dilemma.膀胱假肉瘤性肌纤维母细胞性病变:一种罕见的实体,具有诊断挑战性和治疗困境。
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