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膀胱炎性肌纤维母细胞瘤:一例报告。

Inflammatory Myofibroblastic Tumor of the urinary bladder: A case report.

作者信息

Lassiter Samuel, Smith Michael L, Siegert James, Nguyen Thai

机构信息

Lake Erie College of Osteopathic Medicine, United States.

Franciscan Health Olympia Fields, United States.

出版信息

Urol Case Rep. 2024 Apr 24;54:102726. doi: 10.1016/j.eucr.2024.102726. eCollection 2024 May.

DOI:10.1016/j.eucr.2024.102726
PMID:38799732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11126942/
Abstract

Inflammatory Myofibroblastic Tumors represent a rare subset of spindle cell tumors that can occur in the genitourinary tract, most commonly within the bladder. These tumors are proposed to fall in a spectrum of benign inflammatory pseudotumors to true sarcomas. This, along with their rarity makes diagnosis and treatment challenging to clinicians. We present a 51-year-old female diagnosed with IMT of the bladder following a presentation for hematuria. Treatment consisted of transurethral resection of the tumor. This case, and the accompanying review of the literature highlight the need for further research due to lack of clarity for diagnosis and treatment.

摘要

炎性肌纤维母细胞瘤是梭形细胞瘤的一个罕见亚型,可发生于泌尿生殖道,最常见于膀胱。这些肿瘤被认为处于良性炎性假瘤到真正肉瘤的范围内。这一点以及它们的罕见性使得临床医生在诊断和治疗方面面临挑战。我们报告一例51岁女性,因血尿就诊后被诊断为膀胱炎性肌纤维母细胞瘤。治疗包括经尿道肿瘤切除术。该病例以及附带的文献综述强调,由于诊断和治疗尚不清楚,需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e02/11126942/228d61df88e5/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e02/11126942/75970a34142c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e02/11126942/441653de4af7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e02/11126942/228d61df88e5/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e02/11126942/75970a34142c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e02/11126942/441653de4af7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e02/11126942/228d61df88e5/gr3.jpg

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本文引用的文献

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A Conservative Approach to Inflammatory Myofibroblastic Tumor of the Bladder: A Case Report and Review of Literature.膀胱炎性肌纤维母细胞瘤的保守治疗方法:一例病例报告及文献综述
Case Rep Urol. 2021 Mar 8;2021:6660356. doi: 10.1155/2021/6660356. eCollection 2021.
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Inflammatory myofibroblastic tumors of the urinary bladder: a systematic review.膀胱炎性肌纤维母细胞瘤:一项系统综述
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Inflammatory myofibroblastic tumours of the urinary bladder: multi-centre 18-year experience.
膀胱炎性肌纤维母细胞瘤:多中心18年经验
Urol Int. 2015;94(1):31-6. doi: 10.1159/000358732. Epub 2014 Jul 18.
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Low-grade myofibroblastic proliferations of the urinary bladder.膀胱低度肌纤维母细胞增生。
Arch Pathol Lab Med. 2013 Aug;137(8):1117-28. doi: 10.5858/arpa.2012-0326-RA.
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Utility of ALK-1 protein expression and ALK rearrangements in distinguishing inflammatory myofibroblastic tumor from malignant spindle cell lesions of the urinary bladder.ALK-1蛋白表达及ALK重排在鉴别膀胱炎性肌纤维母细胞瘤与恶性梭形细胞病变中的应用
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Inflammatory myofibroblastic tumors of the urinary tract: a clinicopathologic study of 46 cases, including a malignant example inflammatory fibrosarcoma and a subset associated with high-grade urothelial carcinoma.尿路炎性肌纤维母细胞瘤:46例临床病理研究,包括1例恶性炎性纤维肉瘤及1例与高级别尿路上皮癌相关的亚型。
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Inflammatory pseudotumor and sarcoma of urinary bladder: differential diagnosis and outcome in thirty-eight spindle cell neoplasms.膀胱炎性假瘤与肉瘤:38例梭形细胞肿瘤的鉴别诊断及预后
Mod Pathol. 2001 Oct;14(10):1043-51. doi: 10.1038/modpathol.3880434.
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Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor). A clinicopathologic and immunohistochemical study of 84 cases.肺外炎性肌纤维母细胞瘤(炎性假瘤)。84例临床病理及免疫组化研究。
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