Mayo Clinic Rochester, Rochester, MN, USA.
J Prim Care Community Health. 2021 Jan-Dec;12:21501327211005895. doi: 10.1177/21501327211005895.
A healthy 33 year old male presented in December with a 3 week history of fever and fatigue. He had been deer-hunting in northern Minnesota 1 month prior and had sustained a tick bite. Extensive laboratory investigations and a lumbar puncture were conducted. He was empirically with doxycycline and had rapid improvement in his symptoms. Subsequently, PCR and serologic testing returned positive for Anaplasma phagocytophlium. Anaplasmosis is a tick-borne illness caused by the bacterium Anaplasma phagocytophilum and is typically seen in the warmer months. This patient's presentation in December was uncommon for a tick-borne illness in Minnesota. Regional weather records demonstrated unseasonably warm temperatures during the patient's trip. Ixodes ticks are known to be sensitive to temperature and humidity, which likely contributed to increased tick activity, leading to disease transmission. This case highlights the importance for clinicians to be aware of local weather patterns and how this might influence seasonal disease presentations.
一位 33 岁健康男性于 12 月就诊，主诉发热和乏力 3 周。1 个月前他在明尼苏达州北部狩猎时被蜱虫叮咬。进行了广泛的实验室检查和腰椎穿刺。他经验性地接受了强力霉素治疗，症状迅速改善。随后，PCR 和血清学检测结果显示嗜吞噬细胞无形体阳性。无形体病是一种由嗜吞噬细胞无形体引起的蜱传疾病，通常在温暖的月份出现。这位患者 12 月的表现在明尼苏达州的蜱传疾病中并不常见。当地的天气记录显示，患者旅行期间的气温异常高。已知壁虱对温度和湿度敏感，这可能导致壁虱活动增加，从而导致疾病传播。本病例强调了临床医生了解当地天气模式的重要性，以及这可能如何影响季节性疾病的表现。
