School of Medicine, Yale University, New Haven, Connecticut, 06510.
Dermatology and Laser, Surgery Center, New York, New York, 10028.
Lasers Surg Med. 2021 Oct;53(8):1026-1031. doi: 10.1002/lsm.23397. Epub 2021 Mar 25.
Treatment modalities have been developed to address patient concerns with skin laxity and focal adipose excess. A previously published multicenter clinical trial reported improvement in cellulite severity after a single dermal and subcutaneous treatment on the upper thigh with a microneedle radiofrequency device. In the current study, this device was used to improve the esthetic appearance of body skin laxity and localized fat deposits above the knee, upper arms, and upper-mid back/axillary region ("bra-line").
STUDY DESIGN/MATERIALS AND METHODS: Subjects with cellulite, skin laxity, and/or subcutaneous adipose excess in the suprapatellar region of the anterior thigh, upper arms, and bra-line underwent a single dermal and/or subcutaneous treatment. Investigators and subjects assessed outcome at 1-, 3-, and 6-month follow-up, using 5-point Likert scales for global esthetic improvement, skin laxity improvement, and satisfaction.
In total, 31 females (mean age 51 ± 9 years) with Fitzpatrick skin types I-IV received a single treatment on 62 treatment areas: 22 upper arms, 34 suprapatellar, and 6 bra-lines. Investigator assessments at 1, 3, and 6 months for global esthetic improvement and skin laxity for the upper arms and bra-line demonstrated improvements in 100% of subjects at all timepoints; for the suprapatellar region, these values were 69%, 92%, 65%, and 85%, 92%, 65%, respectively. Investigator satisfaction at each timepoint was satisfied or very satisfied in 80%, 100%, 90% for upper arms; 80%, 80%, 80% for bra-line; and 50%, 81%, 65% for suprapatellar region. Subject self-assessments at 1, 3, and 6 months for global esthetic improvement and skin laxity for the upper arms demonstrated improvements in 100% of subjects at all timepoints; for the bra-line, these values were 40%, 60%, 80%, and 60%, 60%, 80%, respectively; for the suprapatellar region, these values were 81%, 92%, 88%, and 69%, 85%, 88%, respectively. Subject satisfaction at each timepoint was satisfied or very satisfied in 80%, 100%, 100% for upper arms; 40%, 40%, 80% for bra-line; and 50%, 77%, 65% for suprapatellar. Treatments were well tolerated with subjects reporting transient erythema and edema associated with 69% and 46% of treatments, respectively. Mild bruising, resolving within 5 days, was reported after 32% of the treatments.
Microneedle fractional radiofrequency provides a single treatment protocol to improve the esthetic appearance of body skin laxity and localized adipose excess to the upper arms, bra-line, and suprapatellar regions. Further study is warranted to evaluate the degree of improvement and long-term effect beyond 6 months post-treatment. Lasers Surg. Med. © 2021 The Authors. Lasers in Surgery and Medicine published by Wiley Periodicals LLC.
已经开发出多种治疗方式来解决患者对皮肤松弛和局部脂肪过多的担忧。先前发表的一项多中心临床试验报告称，在上大腿使用微针射频设备进行单次真皮和皮下治疗后，可改善橘皮样外观严重程度。在当前的研究中，该设备用于改善膝上、上臂和上背部/腋窝区域（“胸罩线”）的身体皮肤松弛和局部脂肪堆积的美容效果。
研究设计/材料和方法：患有橘皮样外观、皮肤松弛和/或上大腿前侧、上臂和胸罩线部位皮下脂肪过多的患者接受单次真皮和/或皮下治疗。研究人员和患者在 1、3 和 6 个月的随访中使用 5 分李克特量表评估整体美学改善、皮肤松弛改善和满意度。
共有 31 名女性（平均年龄 51±9 岁），Fitzpatrick 皮肤类型 I-IV，在上臂、上大腿和胸罩线的 62 个治疗部位接受单次治疗：22 个在上臂，34 个在上大腿，6 个在胸罩线。1、3 和 6 个月时，研究人员对上臂和胸罩线的整体美学改善和皮肤松弛的评估显示，所有时间点的受试者均有 100%改善；在上大腿，这些值分别为 69%、92%、65%和 85%、92%、65%。各时间点研究人员对满意度的评估均为 80%、100%、90%表示满意或非常满意；80%、80%、80%表示满意或非常满意；50%、81%、65%表示满意或非常满意。1、3 和 6 个月时，患者对上臂的整体美学改善和皮肤松弛的自我评估显示，所有时间点的受试者均有 100%改善；在胸罩线，这些值分别为 40%、60%、80%和 60%、60%、80%；在上大腿，这些值分别为 81%、92%、88%和 69%、85%、88%。各时间点患者对满意度的评估均为 80%、100%、100%表示满意或非常满意；40%、40%、80%表示满意或非常满意；50%、77%、65%表示满意或非常满意。治疗后 69%和 46%的治疗部位分别出现短暂红斑和水肿，治疗耐受性良好。32%的治疗部位出现轻度瘀斑，5 天内消退。
微针分数射频提供了一种单一的治疗方案，可改善上臂、胸罩线和上大腿的身体皮肤松弛和局部脂肪过多的美容效果。需要进一步研究以评估治疗后 6 个月以上的改善程度和长期效果。激光外科学与医学。© 2021 作者。 Wiley Periodicals LLC 出版的《激光外科与医学》。
