[Short-term radiotherapy with 5 × 5 Gy followed by preoperative chemotherapy and resection in patients with locally advanced rectal carcinoma results in improved disease-free survival].
作者信息
Kirste Simon, Fokas Emmanouil, Rödel Claus
机构信息
Klinik für Strahlenheilkunde, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Robert-Koch-Straße 6, 79106, Freiburg, Deutschland.
Klinik für Strahlentherapie und Onkologie, Universitätsklinikum Frankfurt, Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Deutschland.
出版信息
Strahlenther Onkol. 2021 Jun;197(6):567-569. doi: 10.1007/s00066-021-01763-8. Epub 2021 Mar 25.
Abstract
摘要
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Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial.短程放疗联合化疗后行全直肠系膜切除术（TME）与术前放化疗、TME 及辅助化疗在局部进展期直肠癌（RAPIDO）中的应用：一项随机、开放标签、3 期临床试验。
Lancet Oncol. 2021 Jan;22(1):29-42. doi: 10.1016/S1470-2045(20)30555-6. Epub 2020 Dec 7.
2
Compliance and tolerability of short-course radiotherapy followed by preoperative chemotherapy and surgery for high-risk rectal cancer - Results of the international randomized RAPIDO-trial.短程放疗联合术前化疗和手术治疗高危直肠癌的依从性和耐受性 - 国际随机 RAPIDO 试验结果。
Radiother Oncol. 2020 Jun;147:75-83. doi: 10.1016/j.radonc.2020.03.011. Epub 2020 Mar 30.
3
Total Neoadjuvant Therapy in Rectal Cancer: A Systematic Review and Meta-analysis of Treatment Outcomes.直肠癌的新辅助治疗：治疗结果的系统评价和荟萃分析。
Ann Surg. 2020 Mar;271(3):440-448. doi: 10.1097/SLA.0000000000003471.
4
Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12.随机 II 期临床试验：新辅助放化疗联合诱导或巩固化疗治疗局部进展期直肠癌：CAO/ARO/AIO-12。
J Clin Oncol. 2019 Dec 1;37(34):3212-3222. doi: 10.1200/JCO.19.00308. Epub 2019 May 31.
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