Department of General Practice, University of Poitiers, France: 3 rue de la Milétrie, 86000, Poitiers, France.
CESP Centre for research in Epidemiology and Population Health, U1018, Gender, Sexuality and Health team, University Paris-Saclay, University Paris-Sud, UVSQ, Villejuif, Ined, France.
BMC Public Health. 2021 Mar 25;21(1):595. doi: 10.1186/s12889-021-10603-4.
Many countries currently recommend that screening for cervical cancer begin at the age of 25 years. Premature screening (before that age) could lead to unnecessary follow-up examinations and procedures that turn out to be useless. Our objective is to ascertain if the use of particular contraceptive methods are associated with premature screening.
This cross-sectional study based on the CONSTANCES cohort enabled us to include 4297 women younger than 25 years. The factors associated with premature screening were modeled by logistic regression. Missing data were handled by multiple imputations. The multivariate analyses were adjusted for sex life, social and demographic characteristics, and health status.
Nearly half (48.5%) the women younger than 25 years had already undergone premature screening. Women not using contraceptives (aOR 0.3, 95% CI 0.3-0.5) and those using nonmedicalized contraceptives (condom, spermicide, etc.) (aOR 0.5, 95% CI 0.4-0.6) had premature screening less often than women using birth control pills. Higher risks of premature screening were observed in 20-year-old women (aOR 2.7, 95% CI 2.2-3.3) and in those with more than 5 lifetime partners (aOR 2.5, 95% CI 2.0-3.1), compared respectively with women who were younger and those with 5 or fewer lifetime partners.
Young women using contraceptives that require a doctor's prescription are exposed to premature screening more often than those not using contraception and those with nonmedicalized contraceptives.
许多国家目前建议 25 岁开始进行宫颈癌筛查。过早的筛查(在此年龄之前)可能导致不必要的随访检查和无用的程序。我们的目的是确定特定避孕方法的使用是否与过早的筛查有关。
本研究基于 CONSTANCES 队列的横断面研究,纳入了 4297 名年龄小于 25 岁的女性。通过逻辑回归模型对与过早筛查相关的因素进行建模。缺失数据采用多重插补处理。多变量分析调整了性生活、社会人口特征和健康状况。
近一半(48.5%)年龄小于 25 岁的女性已经进行了过早的筛查。未使用避孕药具的女性(比值比 0.3,95%置信区间 0.3-0.5)和使用非医学化避孕药具(避孕套、杀精剂等)的女性(比值比 0.5,95%置信区间 0.4-0.6)进行过早筛查的可能性低于使用避孕药具的女性。20 岁的女性(比值比 2.7,95%置信区间 2.2-3.3)和有 5 个以上性伴侣的女性(比值比 2.5,95%置信区间 2.0-3.1)进行过早筛查的风险较高,分别与年龄较小和有 5 个或更少性伴侣的女性相比。
使用需要医生处方的避孕药具的年轻女性比不使用避孕药具和使用非医学化避孕药具的女性更容易进行过早的筛查。