良性乳腺疾病中的焦虑与抑郁研究
A Study of Anxiety and Depression in Benign Breast Disease.
作者信息
Srivastava Vivek, Meena Rakesh Kumar, Ansari Mumtaz A, Kumar Dheeraj, Kumar Anand
机构信息
Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
出版信息
J Midlife Health. 2020 Oct-Dec;11(4):200-209. doi: 10.4103/jmh.JMH_85_20. Epub 2021 Jan 21.
BACKGROUND
To compare the prevalence of anxiety and depression levels in patients with benign breast disease (BBD) and healthy individuals using Hospital Anxiety and Depression Scale (HADS) and Brief Patient Health Questionnaire (BPHQ).
METHODS
This study includes 100 patients who were clinically suspected of having BBDs and were matched against 100 healthy age-matched controls from June 2016 and July 2018. The diagnosis of BBD was established on the basis of ultrasonography, fine needle aspiration cytology, and/or histopathology. For the diagnosis of anxiety and depression, BPHQ was used and the level of anxiety and depression was measured using the HADS. The questionnaire at both prediagnosis and at follow-up assessment after 3 months was done.
RESULTS
On comparing anxiety and depression using BPHQ score among cases and controls, both were significantly associated with cases than controls ( < 0.001 and = 0.0016, respectively). On comparing anxiety and depression using HADS score, there was a significant difference (median) in both anxiety and depression level between cases and controls ( < 0.001 and < 0.001, respectively). After 3 months of follow-up, there was a significant improvement in anxiety and depression scores by both BPHQ ( = 0.007 and = 0.0016) and HADS ( < 0.001 and < 0.001). The 3-month follow-up data showed a significant improvement in BPHQ (depression) score in patients with breast lump and mastalgia ( = 0.001 and = 0.008). The HADS (anxiety score) showed significant improvement in patients presenting with diseases/aberrations other than fibroadenoma while the HADS (depression) score showed a significant improvement in all except fibroadenosis present either alone or along with fibroadenoma. The HADS (depression) score showed a significant improvement in fibroadenoma, others group, breast lump, and mastalgia ( = 0.040, = 0.005, < 0.001, and = 0.025, respectively).
CONCLUSION
Indian female patients who present with BBDs are also affected by anxiety and depression.
背景
使用医院焦虑抑郁量表（HADS）和简易患者健康问卷（BPHQ）比较乳腺良性疾病（BBD）患者与健康个体的焦虑和抑郁水平患病率。
方法
本研究纳入了2016年6月至2018年7月期间100例临床疑似患有BBD的患者，并与100例年龄匹配的健康对照者进行匹配。BBD的诊断基于超声检查、细针穿刺细胞学检查和/或组织病理学检查。对于焦虑和抑郁的诊断，使用BPHQ，并使用HADS测量焦虑和抑郁水平。在诊断前以及3个月后的随访评估时均进行问卷调查。
结果
使用BPHQ评分比较病例组和对照组的焦虑和抑郁情况，两者与病例组的相关性均显著高于对照组（分别为P<0.001和P = 0.0016）。使用HADS评分比较焦虑和抑郁情况，病例组和对照组在焦虑和抑郁水平上均存在显著差异（分别为P<0.001和P<0.001）。随访3个月后，BPHQ（P = 0.007和P = 0.0016）和HADS（P<0.001和P<0.001）的焦虑和抑郁评分均有显著改善。3个月的随访数据显示，乳腺肿块和乳腺疼痛患者的BPHQ（抑郁）评分有显著改善（P = 0.001和P = 0.008）。HADS（焦虑评分）显示，除纤维腺瘤外患有其他疾病/病变的患者有显著改善，而HADS（抑郁）评分显示，除单独或合并纤维腺瘤的纤维腺病外，所有患者均有显著改善。HADS（抑郁）评分在纤维腺瘤、其他组、乳腺肿块和乳腺疼痛患者中均有显著改善（分别为P = 0.040、P = 0.005、P<0.001和P = 0.025）。
结论
患有BBD的印度女性患者也受到焦虑和抑郁的影响。
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