Department of Medical Oncology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Department of Medical Oncology, Consorcio Hospitalario Provincial de Castellón, Castellón de la Plana, Spain.
Clin Transl Oncol. 2021 May;23(5):931-939. doi: 10.1007/s12094-021-02580-2. Epub 2021 Mar 25.
Anaemia is defined by the presence of haemoglobin (Hb) levels < 13 g/dL in men and 12 g/dL in women. Up to 39% of cancer patients present it at the time of diagnosis and up to 40% have iron deficiency. Anaemia causes fatigue, functional deterioration and a reduction in the quality of life; it has also been associated with a poorer response to anti-tumour treatment and lower survival. Basic diagnostic tests for anaemia are simple and should be a routine part of clinical practice. These guidelines review the available evidence on the use of different therapies for treating anaemia: erythropoiesis-stimulating agents, iron supplements, and transfusion of blood products.
贫血的定义为男性血红蛋白（Hb）水平<13 g/dL，女性<12 g/dL。多达 39%的癌症患者在诊断时存在贫血，多达 40%的患者存在缺铁。贫血可导致疲劳、功能恶化和生活质量下降；它还与抗肿瘤治疗反应较差和生存率降低有关。贫血的基本诊断测试很简单，应该成为临床实践的常规部分。本指南回顾了不同治疗贫血疗法的可用证据：红细胞生成刺激剂、铁补充剂和血液制品输注。
