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SEOM 临床指南:癌症患者贫血治疗(2020 年)。

SEOM clinical guidelines for anaemia treatment in cancer patients (2020).

机构信息

Department of Medical Oncology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Department of Medical Oncology, Consorcio Hospitalario Provincial de Castellón, Castellón de la Plana, Spain.

出版信息

Clin Transl Oncol. 2021 May;23(5):931-939. doi: 10.1007/s12094-021-02580-2. Epub 2021 Mar 25.

Abstract

Anaemia is defined by the presence of haemoglobin (Hb) levels < 13 g/dL in men and 12 g/dL in women. Up to 39% of cancer patients present it at the time of diagnosis and up to 40% have iron deficiency. Anaemia causes fatigue, functional deterioration and a reduction in the quality of life; it has also been associated with a poorer response to anti-tumour treatment and lower survival. Basic diagnostic tests for anaemia are simple and should be a routine part of clinical practice. These guidelines review the available evidence on the use of different therapies for treating anaemia: erythropoiesis-stimulating agents, iron supplements, and transfusion of blood products.

摘要

贫血的定义为男性血红蛋白(Hb)水平<13 g/dL,女性<12 g/dL。多达 39%的癌症患者在诊断时存在贫血,多达 40%的患者存在缺铁。贫血可导致疲劳、功能恶化和生活质量下降;它还与抗肿瘤治疗反应较差和生存率降低有关。贫血的基本诊断测试很简单,应该成为临床实践的常规部分。本指南回顾了不同治疗贫血疗法的可用证据:红细胞生成刺激剂、铁补充剂和血液制品输注。

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