Katoh T, Nakai T, Hayashi S, Satake T
Department of Surgery, Nagoya Ekisaikai Hospital, Aichi, Japan.
Am J Gastroenterol. 1988 Jun;83(6):670-4.
We report a case of noninvasive carcinoma of the gallbladder arising in the surface mucosa of localized type adenomyomatosis. It was first detected as a polypoid lesion during routine examination with ultrasonography. The gross appearance of the resected specimen showed localized type adenomyomatosis with multiple cysts containing mucin at the fundus of the gallbladder. Microscopic study revealed noninvasive carcinoma in its surface mucosa associated with papillary adenoma in the cyst wall. The occurrence of carcinoma in adenomyomatosis is very rare, and only a few cases have been reported in the literature. Although it has been generally accepted that there is no fear of malignant transformation of adenomyomatosis, the present case suggested that it might be a possible candidate for carcinoma.
我们报告一例起源于局限性腺肌增生症表面黏膜的胆囊非浸润性癌。它最初是在超声常规检查时作为息肉样病变被发现的。切除标本的大体外观显示为局限性腺肌增生症，胆囊底部有多个含黏液的囊肿。显微镜检查显示其表面黏膜有非浸润性癌，囊肿壁伴有乳头状腺瘤。腺肌增生症中发生癌非常罕见，文献中仅报道了少数病例。尽管一般认为腺肌增生症无需担心恶变，但本病例提示它可能是癌的一个潜在候选者。
