Kurihara K, Mizuseki K, Ninomiya T, Shoji I, Kajiwara S
Department of Pathology, Uwajima City Hospital, Japan.
Acta Pathol Jpn. 1993 Jan-Feb;43(1-2):82-5. doi: 10.1111/j.1440-1827.1993.tb02919.x.
We describe a case of well differentiated adenocarcinoma of the gall-bladder that arose from a localized type of adenomyomatosis. Grossly, the cancer was located in the fundus and exhibited a polypoid and well demarcated nodule with multiple small cysts. Histologically, the nodule consisted of glandular structures and stroma containing bundles of smooth muscle cells. The glandular epithelia were varied in appearance, ranging from malignant to benign glands. The adenocarcinoma was limited to the nodule, with normal surface mucosal epithelia and without obvious stromal invasion.
我们描述了一例起源于局限性腺肌病的高分化胆囊腺癌病例。大体上，肿瘤位于胆囊底部，表现为息肉样且边界清晰的结节，伴有多个小囊肿。组织学上，该结节由腺管结构和含有平滑肌细胞束的间质组成。腺上皮外观各异，从恶性腺体到良性腺体都有。腺癌局限于结节内，表面黏膜上皮正常，无明显的间质浸润。
