中国人消费木薯摄入氰化物的膳食暴露与风险评估。
Dietary exposure and risk assessment of cyanide via cassava consumption in Chinese population.
机构信息
College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Key Laboratory for Agro-Products Nutritional Evaluation of Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-Products Postharvest Handling of Ministry of Agriculture and Rural Affairs, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang International Scientific and Technological Cooperation Base of Health Food Manufacturing and Quality Control, Zhejiang University, Hangzhou 310058, China; Fuli Institute of Food Science, Zhejiang University, Hangzhou 310058, China; Ningbo Research Institute, Zhejiang University, Ningbo 315100, China.
Analysis Center of Agrobiology and Environmental Sciences, Zhejiang University, Hangzhou 310058, China.
出版信息
Food Chem. 2021 Aug 30;354:129405. doi: 10.1016/j.foodchem.2021.129405. Epub 2021 Mar 1.
The intake of cassava would probably induce adverse health effects since there are toxic cyanide in cassava. However, the risk assessment of cassava consumption has not been reported in China. Therefore, this paper aimed to evaluate the dietary risks of cassava cyanide and proposed a maximum residue limit (MRL) for cyanogenic glycosides (CNGs) in cassava. The retention rate of CNGs and CN were 61% and 11% after boiling, respectively. The acute dietary exposure of CN and CNGs were 0.6-fold and 1.7-fold of acute risk reference dose, respectively. There was no chronic health risk across all populations concerning cassava consumption. The MRL of CNGs was proposed as 200 mg/kg in cassava. Risk assessment of cyanide for foods rich in CNGs was suggested to be based on CNGs quantification rather than that of CN.
由于木薯中含有有毒的氰化物，因此食用木薯可能会对健康产生不良影响。然而，目前尚未有中国国内关于食用木薯风险评估的报道。因此，本文旨在评估木薯氰化物的膳食风险，并提出木薯中氰苷（CGNs）的最大残留限量（MRL）。经煮沸后，CGNs 和 CN 的保留率分别为 61%和 11%。急性膳食暴露中，CN 和 CGNs 分别为急性参考剂量的 0.6 倍和 1.7 倍。对于所有人群，食用木薯均不存在慢性健康风险。建议木薯中 CGNs 的 MRL 为 200mg/kg。对于富含 CGNs 的食物中的氰化物风险评估，建议基于 CGNs 的定量分析，而不是 CN。
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