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Development of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: A guide and case study in setting up an emergency-use, laboratory-developed molecular assay.用于检测新型冠状病毒(SARS-CoV-2)的定性实时逆转录聚合酶链反应(RT-PCR)检测方法的开发:建立紧急使用的实验室自行研发分子检测方法的指南及案例研究
medRxiv. 2020 Sep 1:2020.08.26.20157297. doi: 10.1101/2020.08.26.20157297.
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Assessment of COVID-19 Hospitalizations by Race/Ethnicity in 12 States.12 个州的基于种族/族裔的 COVID-19 住院评估。
JAMA Intern Med. 2021 Jan 1;181(1):131-134. doi: 10.1001/jamainternmed.2020.3857.
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Race/Ethnicity, Underlying Medical Conditions, Homelessness, and Hospitalization Status of Adult Patients with COVID-19 at an Urban Safety-Net Medical Center - Boston, Massachusetts, 2020.种族/民族、潜在医疗状况、无家可归和住院状态的 COVID-19 成年患者在城市安全网医疗中心-马萨诸塞州波士顿,2020 年。
MMWR Morb Mortal Wkly Rep. 2020 Jul 10;69(27):864-869. doi: 10.15585/mmwr.mm6927a3.
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Prevalence and Severity of Coronavirus Disease 2019 (COVID-19) Illness in Symptomatic Pregnant and Postpartum Women Stratified by Hispanic Ethnicity.按西班牙裔种族分层的有症状孕妇和产后妇女中2019冠状病毒病(COVID-19)的患病率和严重程度
Obstet Gynecol. 2020 Aug;136(2):300-302. doi: 10.1097/AOG.0000000000004005.
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The Early Natural History of SARS-CoV-2 Infection: Clinical Observations From an Urban, Ambulatory COVID-19 Clinic.新型冠状病毒2型感染的早期自然史:来自一家城市门诊COVID-19诊所的临床观察
Mayo Clin Proc. 2020 Jun;95(6):1124-1126. doi: 10.1016/j.mayocp.2020.04.010. Epub 2020 Apr 20.
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Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China.肥胖与 2019 年冠状病毒病严重程度在深圳市某定点医院的相关性研究
Diabetes Care. 2020 Jul;43(7):1392-1398. doi: 10.2337/dc20-0576. Epub 2020 May 14.
7
Development and Validation of a Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19.开发和验证一种临床风险评分,以预测 COVID-19 住院患者发生危重症的情况。
JAMA Intern Med. 2020 Aug 1;180(8):1081-1089. doi: 10.1001/jamainternmed.2020.2033.
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Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area.在纽约市地区,5700 名因 COVID-19 住院的患者的特征、合并症和结局。
JAMA. 2020 May 26;323(20):2052-2059. doi: 10.1001/jama.2020.6775.
9
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.《武汉 2019 年新型冠状病毒感染的肺炎 138 例住院患者临床特征分析》
JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585.

马萨诸塞州社区门诊新冠患者住院的风险因素:疫情初期激增期间。

Risk Factors for Hospitalization Among Patients with COVID-19 at a Community Ambulatory Clinic in Massachusetts During the Initial Pandemic Surge.

机构信息

Harvard Medical School, Cambridge Health Alliance, Somerville, 236 Highland Ave, Somerville, Boston, MA, 02143, USA.

Department of Medicine, Cambridge Health Alliance, Somerville, Harvard Medical School, Boston, MA, USA.

出版信息

J Immigr Minor Health. 2021 Oct;23(5):1110-1115. doi: 10.1007/s10903-021-01189-5. Epub 2021 Mar 26.

DOI:10.1007/s10903-021-01189-5
PMID:33772419
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7996715/
Abstract

Among patients with COVID-19 evaluated in outpatient settings, factors associated with hospitalization remain poorly understood. Multivariable regressions were used to assess sociodemographic and clinical factors associated with increased odds of hospitalization among patients with confirmed COVID-19 between March 18, 2020 through April 25, 2020 at a community-based outpatient clinic in Massachusetts. Older age, BMI ≥ 25, self-reported dizziness/lightheadedness, temperature ≥ 99.5°F, tachycardia, and oxygen saturation < 95% were associated with increased odds of hospitalization after adjustment for age, sex, and BMI. There was also an association between speaking Spanish as primary language and increased odds of hospitalization (compared to English, adjusted OR = 2.99 [95% CI 1.39, 6.39]). Speaking Portuguese as primary language was not associated with increased odds of hospitalization (compared to English, adjusted OR = 1.83 [0.78, 4.28]). In addition to several clinical risk factors established among inpatients, our study found that primarily speaking Spanish, but not Portuguese, was a marker of hospitalization risk among a diverse outpatient cohort of patients with COVID-19.

摘要

在门诊环境中评估的 COVID-19 患者中,与住院相关的因素仍了解甚少。多变量回归用于评估 2020 年 3 月 18 日至 4 月 25 日在马萨诸塞州一家社区门诊诊所中确诊 COVID-19 患者的社会人口统计学和临床因素与住院几率增加之间的关联。在调整年龄、性别和 BMI 后,年龄较大、BMI≥25、自述头晕/头晕、体温≥99.5°F、心动过速和血氧饱和度<95%与住院几率增加相关。主要讲西班牙语也与住院几率增加相关(与英语相比,调整后的 OR = 2.99[95%CI 1.39,6.39])。主要讲葡萄牙语与住院几率增加无关(与英语相比,调整后的 OR = 1.83[0.78,4.28])。除了在住院患者中确定的几个临床危险因素外,我们的研究还发现,主要讲西班牙语,而不是葡萄牙语,是 COVID-19 门诊患者多样化队列中住院风险的标志。