Department of Surgery, Faculty Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University, Prague, Czech Republic.
Faculty of Biomedical Engineering CTU in Prague, Kladno, Czech Republic.
Int Wound J. 2022 Jan;19(1):29-35. doi: 10.1111/iwj.13593. Epub 2021 Mar 27.
Ideal dressings of surgical wounds should provide moist, semi-permeable, and antiseptic environments for optimal wound healing. To maximise patient comfort, surgical dressings must be hypoallergenic, not restrict movement, and allow patients to manage their personal hygiene. From the aspect of health care personnel, dressings should enable visual monitoring of the wound without the need for removing them, thus reducing the number of dressing changes. The active antimicrobial effect of silver cations has been demonstrated by many studies. StopBac is a unique surgical dressing based on the sol-gel process. Silver cations are bound in a colloidal solution in an organic-inorganic hybrid organosilicate oligomer. This gel is deposited on a pad using spray atomisation. The result is a polymer nanolayer matrix with prolonged and controlled release of silver ions. This pad forms part of a waterproof hypoallergenic transparent adhesive bandage. The goal of this study was to prospectively evaluate the ability of StopBac to prevent surgical site infections (SSIs) in patients after abdominal surgery. The secondary goal was to compare costs and determine the properties of this new material. A total of 32 patients were included in the study. The patients were followed up until their surgical wounds healed completely. An SSI occurred only in one patient.
理想的外科伤口敷料应提供湿润、半透性和抗菌环境，以实现最佳的伤口愈合。为了最大限度地提高患者的舒适度，外科敷料必须是低敏的，不会限制运动，并且允许患者管理自己的个人卫生。从医护人员的角度来看，敷料应能够在不取下的情况下进行目视监测，从而减少更换敷料的次数。许多研究已经证明了银离子的主动抗菌作用。StopBac 是一种基于溶胶-凝胶工艺的独特的外科敷料。银离子在有机-无机杂化有机硅烷低聚物的胶体溶液中结合。这种凝胶通过喷雾雾化沉积在垫上。结果是形成具有延长和控制释放银离子的聚合物纳米层基质。该垫是防水、低敏透明粘性绷带的一部分。本研究的目的是前瞻性评估 StopBac 在腹部手术后预防患者手术部位感染（SSI）的能力。次要目标是比较成本并确定这种新材料的特性。共有 32 名患者入组本研究。患者随访至手术伤口完全愈合。只有一名患者发生 SSI。
