Wang Yuanyuan, Wang Huan, Li Zhixian, Yang Dongjie, Qiu Xueqing, Liu Yechen, Yan Mengzhen, Li Qiong
School of Chemistry and Chemical Engineering, Guangdong Provincial Engineering Research Center for Green Fine Chemicals, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou 510641, China.
School of Chemistry and Chemical Engineering, Guangdong Provincial Engineering Research Center for Green Fine Chemicals, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou 510641, China; State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou 510641, China.
J Colloid Interface Sci. 2021 Jul 15;594:316-325. doi: 10.1016/j.jcis.2021.03.033. Epub 2021 Mar 15.
Lignin has been demonstrated to be green and effective for the modification of ZnO-based materials. In this work, quaternized lignin/zinc oxide nanostructured hybrid composites (QLS/ZnO NCs) were synthesized with good dispersion and uniform particle size via a facile hydrothermal method. Sodium lignosulfonate (LS) was modified by quaternization to endow the positive charges, which effectively captured bacteria due to the electrostatic interactions. Interestingly, QLS/ZnO NCs show a litchi-like morphology consisting of nanorods with diameters of 5-10 nm, which further resulted in damage to the bacterial cell membrane. Owing to the surface charge and rough surface topology for bacterial capture, QLS/ZnO NCs exhibited greatly enhanced antibacterial activity compared with bare ZnO. After being treated with QLS/ZnO NCs for 90 min, the sterilization rates of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) reached 97.54% and 99.55%, respectively. Due to the reactive oxygen species (ROS) produced by ZnO under light irradiation, the antibacterial activity of QLS/ZnO NCs could be further enhanced. In addition, the minimal inhibition concentrations (MICs) of QLS/ZnO NCs towards E. coli and S. aureus were both 100 μg/mL, and the minimum bactericidal concentrations (MBCs) were 100 μg/mL and 200 μg/mL, respectively. Moreover, with the incorporation of QLS/ZnO NCs into polyurethane films, the composite films showed excellent antibacterial activity, strong tensile strength and enhanced ultraviolet light blocking performance.
木质素已被证明对氧化锌基材料的改性具有绿色且有效的作用。在本工作中，通过简便的水热法合成了具有良好分散性和均匀粒径的季铵化木质素/氧化锌纳米结构杂化复合材料（QLS/ZnO NCs）。木质素磺酸钠（LS）通过季铵化进行改性以赋予正电荷，由于静电相互作用，其能有效捕获细菌。有趣的是，QLS/ZnO NCs呈现出由直径为5 - 10纳米的纳米棒组成的荔枝状形态，这进一步导致细菌细胞膜受损。由于用于细菌捕获的表面电荷和粗糙的表面拓扑结构，与裸露的氧化锌相比，QLS/ZnO NCs表现出大大增强的抗菌活性。用QLS/ZnO NCs处理90分钟后，大肠杆菌（E. coli）和金黄色葡萄球菌（S. aureus）的杀菌率分别达到97.54%和99.55%。由于氧化锌在光照下产生活性氧（ROS），QLS/ZnO NCs的抗菌活性可进一步增强。此外，QLS/ZnO NCs对大肠杆菌和金黄色葡萄球菌的最小抑菌浓度（MICs）均为100μg/mL，最小杀菌浓度（MBCs）分别为100μg/mL和200μg/mL。而且，将QLS/ZnO NCs掺入聚氨酯薄膜中后，复合薄膜表现出优异的抗菌活性、强大的拉伸强度和增强的紫外线阻隔性能。
