Hughes Kelly, Hussaini Zeba, Shah Mahek K, Hilton Robert, Oxman David
Department of Internal Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
Department of Cardiology, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
Am J Med Sci. 2021 May;361(5):646-649. doi: 10.1016/j.amjms.2020.12.005. Epub 2021 Feb 10.
The SARS-CoV-2 virus, or COVID-19, is responsible for the current global pandemic and has resulted in the death of over 400,000 in the United States. Rates of venous thromboembolism have been noted to be much higher in those infected with COVID-19. Here we report a case-series of COVID-19 patients with diverse presentations of pulmonary embolism (PE). We also briefly describe the pathophysiology and mechanisms for pulmonary embolism in COVID-19. These cases indicate a need to maintain a high index of suspicion for PE in patients with COVID-19, as well as the need to consider occult COVID-19 infection in patients with PE in the right clinical circumstance.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒，即新型冠状病毒肺炎（COVID-19），是当前全球大流行的元凶，已导致美国40多万人死亡。据指出，新型冠状病毒肺炎感染者的静脉血栓栓塞发生率要高得多。在此，我们报告一系列新型冠状病毒肺炎患者出现各种肺栓塞（PE）表现的病例。我们还简要描述了新型冠状病毒肺炎中肺栓塞的病理生理学和机制。这些病例表明，对于新型冠状病毒肺炎患者需要高度怀疑肺栓塞，同时在适当的临床情况下，对于肺栓塞患者也需要考虑隐匿性新型冠状病毒肺炎感染。
