University of Paris, France.
University of Paris, France; AP-HP (Greater Paris University Hospitals), University Hospital Louis Mourier, Psychiatry Department, 92700, Colombes, France; INSERM UMR1266, Institute of Psychiatry and Neurosciences of Paris (IPNP), Paris, France; Fondation FONDAMENTAL, Créteil, France.
Neurosci Biobehav Rev. 2021 Jul;126:252-264. doi: 10.1016/j.neubiorev.2021.03.024. Epub 2021 Mar 24.
Healthcare workers have been facing the COVID-19 pandemic, with numerous critical patients and deaths, and high workloads. Quality of care is related to the mental status of healthcare workers. This PRISMA systematic review and meta-analysis, on Pubmed/Psycinfo up to October 8, 2020, estimates the prevalence of mental health problems among healthcare workers during this pandemic. The systematic review included 70 studies (101 017 participants) and only high-quality studies were included in the meta-analysis. The following pooled prevalences were estimated: 300 % of anxiety (95 %CI, 24.2-37.05); 311 % of depression (95 %CI, 25.7-36.8); 565 % of acute stress (95 %CI - 30.6-80.5); 20,2% of post-traumatic stress (95 %CI, 9.9-33.0); 44.0 % of sleep disorders (95 %CI, 24.6-64.5). The following factors were found to be sources of heterogeneity in subgroups and metaregressions analysis: proportion of female, nurses, and location. Targeted prevention and support strategies are needed now, and early in case of future health crises.
医护人员一直在应对 COVID-19 大流行,面临大量重症患者和死亡病例,以及繁重的工作量。护理质量与医护人员的精神状态有关。这项基于 PubMed/Psycinfo 数据库的 PRISMA 系统评价和荟萃分析,检索时间截至 2020 年 10 月 8 日,旨在评估此次大流行期间医护人员心理健康问题的发生率。系统评价纳入了 70 项研究(101017 名参与者),仅纳入了高质量研究进行荟萃分析。估计的综合患病率为:焦虑症 300%(95%CI,24.2-37.05);抑郁症 311%(95%CI,25.7-36.8);急性应激 565%(95%CI,-30.6-80.5);创伤后应激障碍 20.2%(95%CI,9.9-33.0);睡眠障碍 44.0%(95%CI,24.6-64.5)。亚组分析和荟萃回归分析发现,以下因素是异质性的来源:女性比例、护士和地点。现在需要有针对性的预防和支持策略,并且在未来发生卫生危机时要尽早实施。