Acharya Kshitiz, Poudel Navin, Adhikari Aramva Bikram, Giri Subarna, Bali Kanchana, Bhatta Naveen C
Maharajgunj Medical Campus, Tribhuvan University Institute of Medicine, Maharajgunj, Nepal.
Maharajgunj Medical Campus, Tribhuvan University Institute of Medicine, Maharajgunj, Nepal.
Int J Surg Case Rep. 2021 Apr;81:105820. doi: 10.1016/j.ijscr.2021.105820. Epub 2021 Mar 23.
Myopericytoma is a rare mesenchymal soft tissue tumor that originates from perivascular myoid cells and mostly benign in nature. With a slight male predisposition, it occurs more commonly in the lower extremities with an insidious and painless presentation. Contrary to the usual, our patient was with a rare presentation in the inguinal region with a dull aching pain.
We herein report a case of a 64-year-old female patient with myopericytoma, the first of its kind reported in Nepal, present in the right inguinal region and surgically removed. The mass was single with dull aching pain, non-tender, globular, smooth, mobile, covered with skin and, had been slowly growing for 1 year and had started bleeding for 4 days. On complete surgical excision and subsequent biopsy, a nodule with thin-walled blood vessels and spindle-shaped cells having indistinct cell border, eosinophilic cytoplasm, and oval to spindle-shaped nucleus was observed, features consistent with those of myopericytoma.
Myopericytoma can occur in different sites in the body. Its differential diagnoses in the inguinal region include inguinal hernia, lipoma, or an inguinal lymphangioma. Histopathological analysis and immunohistochemistry (IHC) staining are used for diagnosis and confirmation.
Myopericytomas are rare and have a substantial propensity to be misdiagnosed as other soft tissue tumors such as sarcomas due to significant overlap in their presentation and histological features. Complete surgical excision of mass is the curative therapy.
肌周细胞瘤是一种罕见的间叶性软组织肿瘤，起源于血管周围肌样细胞，本质上大多为良性。男性略多，常见于下肢，起病隐匿且无痛。与通常情况不同的是，我们的患者在腹股沟区表现罕见，伴有隐痛。
我们在此报告一例64岁女性肌周细胞瘤患者，这是尼泊尔首例此类报告，肿瘤位于右侧腹股沟区，已手术切除。肿块为单个，伴有隐痛，无压痛，呈球形，表面光滑，可活动，表面有皮肤覆盖，缓慢生长1年，已出血4天。完整手术切除并随后活检后，观察到一个有薄壁血管和梭形细胞的结节，细胞边界不清，细胞质嗜酸性，细胞核呈椭圆形至梭形，这些特征与肌周细胞瘤一致。
肌周细胞瘤可发生于身体的不同部位。其在腹股沟区的鉴别诊断包括腹股沟疝、脂肪瘤或腹股沟淋巴管瘤。组织病理学分析和免疫组织化学（IHC）染色用于诊断和确诊。
肌周细胞瘤罕见，由于其临床表现和组织学特征有显著重叠，极易被误诊为其他软组织肿瘤，如肉瘤。完整手术切除肿块是治愈性疗法。
