Xia Lili, Chen Yu, Geng Ning, Jiang Jinyan, Yang Mingzhong, Zhang Weiping
Department of Oral Pathology, West China College of Stomatology, Sichuan University, Chengdu, China.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Feb;109(2):e59-62. doi: 10.1016/j.tripleo.2009.09.029.
Myopericytoma is a rare mesenchymal neoplasm with perivascular myoid differentiation. Myopericytoma arises most commonly in middle adulthood. The lesion generally involves the distal extremities; however, tumors can also arise at other sites, including the proximal extremities and head and neck. In this case report, a 43-year-old Chinese woman presented with a painless slowly growing nodule in her right cheek. Biopsy revealed a periluminal proliferation of monomorphic oval to spindle-shaped myoid-appearing cells. Immunohistochemistry showed a positive staining for smooth muscle actin. The clinical, pathologic, and immunohistochemical features are discussed. To our knowledge, this is the first case report in the medical literature of multifocal myopericytoma in the maxillofacial region.
肌周细胞瘤是一种罕见的具有血管周围肌样分化的间叶性肿瘤。肌周细胞瘤最常见于中年。该病变通常累及四肢远端;然而,肿瘤也可发生于其他部位,包括四肢近端以及头颈部。在本病例报告中,一名43岁的中国女性患者右脸颊出现一个无痛性缓慢生长的结节。活检显示在管周有单形性椭圆形至梭形的肌样细胞增生。免疫组织化学显示平滑肌肌动蛋白染色呈阳性。本文讨论了其临床、病理及免疫组织化学特征。据我们所知,这是医学文献中关于颌面部多灶性肌周细胞瘤的首例病例报告。