Department of Radiology, Central Military Hospital Koblenz, 56072, Koblenz, Germany.
Department of Radiology, German Air Force Center of Aerospace Medicine, 82242, Fürstenfeldbruck, Germany.
J Neurol. 2021 Oct;268(10):3777-3780. doi: 10.1007/s00415-021-10440-w. Epub 2021 Mar 27.
Arachnoid cysts (ACs) are frequent incidental findings and may be associated with neuropsychiatric symptoms. Usually growth of the ACs with pressure on adjacent brain tissue is regarded as cause of the symptoms. This study was undertaken to identify if and which ACs grow with time.
We used a large database of cranial MRIs for a retrospective analysis.
During a period of 10 years, we collected 166 ACs of 50 persons, mean observational period was 2.5 years. Among these, only larger cysts at the temporal pole, i.e., Galassi II ACs, grew with a rate of 0.3 ml a year (β = 0.32, SE 0.07, p = 0.003); all other ACs remained constant in size or became smaller. All cysts were clinically silent.
Most ACs remain constant in size or become smaller.
This study provides Class III evidence that the majority of arachnoid cysts does not grow.
蛛网膜囊肿（AC）是常见的偶发发现，可能与神经精神症状相关。通常认为 AC 生长并对邻近脑组织施加压力是导致症状的原因。本研究旨在确定是否以及哪些 AC 会随时间而增长。
我们使用了一个大型的颅 MRI 数据库进行回顾性分析。
在 10 年的时间里，我们收集了 50 名患者的 166 个 AC，平均观察期为 2.5 年。其中，只有颞极较大的囊肿，即 Galassi II AC，以每年 0.3ml 的速度增长（β=0.32，SE 0.07，p=0.003）；所有其他 AC 的大小保持不变或变小。所有囊肿均无临床症状。
大多数 AC 的大小保持不变或变小。
本研究提供了 III 级证据，表明大多数蛛网膜囊肿不会增长。
