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埃及专科高血压诊所注册处:社会经济地位较低的高血压患者中,临床特征和高血压管理方面的性别差异。

Registry of the Egyptian specialized hypertension clinics: Sex-related differences in clinical characteristics and hypertension management among low socioeconomic hypertensive patients.

机构信息

Faculty of Medicine, Department of Cardiology, Helwan University, Cairo, Egypt.

Faculty of Medicine, Department of Cardiology, Cairo University, Cairo, Egypt.

出版信息

J Clin Hypertens (Greenwich). 2021 Jun;23(6):1120-1128. doi: 10.1111/jch.14231. Epub 2021 Mar 28.

Abstract

Hypertension is a major modifiable risk factor for cardiovascular disease (CVD) which is a leading cause of death in developing countries affecting both genders. Gender dissimilarity in clinical characteristics and hypertension (HTN) management among hypertensive patients has been reported in several reports before. The aim was to detect sex differences in clinical characteristics and HTN management among Egyptian hypertensive patients. Data from 4701 hypertensive patients attending 9 university located Specialized Hypertension clinic (SHC) were collected from October 2014 to September 2017. The collected data included demographics, cardiovascular risk profile, hypertension-related history, anthropometric and blood pressure (BP) measurements, antihypertensive medications used, number of patients attending the follow-up visits, and HTN control rate. Females represented 58.5% of the recruited patients, they were younger, with higher BMI, lower education level, and employment rate compared with males. Females had lower mean office systolic and diastolic BP than males (144.2 ± 22.6 vs. 146.5 ± 22.0 mmHg and 88.1 ± 13.0 vs. 89.9 ± 12.6 mmHg, respectively) and lower rate of uncontrolled BP (54.8% vs. 61.1% in males P < .001). Antihypertensive drugs were comparable among both sexes except for angiotensin converting enzyme inhibitors which were more prescribed in males. Compliance to antihypertensive medications was better in females (63.6% vs. 60.1% in males, P = .015). To conclude, Egyptian hypertensive females have different clinical characteristics as compared to their counterpart males with better BP control, adherence to antihypertensive medications, lower systolic and diastolic BP, and no major differences in the prescribed antihypertensive distribution.

摘要

高血压是心血管疾病(CVD)的一个主要可改变的危险因素,在发展中国家,它是导致死亡的主要原因,影响到两性。以前的一些报告已经报道了高血压患者的临床特征和高血压(HTN)管理中存在的性别差异。目的是检测埃及高血压患者的临床特征和 HTN 管理中的性别差异。2014 年 10 月至 2017 年 9 月,从 9 所大学所在地的专门高血压诊所(SHC)收集了 4701 名高血压患者的数据。收集的数据包括人口统计学、心血管风险状况、与高血压相关的病史、人体测量和血压(BP)测量、使用的抗高血压药物、接受随访的患者人数以及 HTN 控制率。女性占招募患者的 58.5%,她们比男性年轻,BMI 更高,受教育程度和就业率更低。女性的诊室收缩压和舒张压均低于男性(144.2 ± 22.6 与 146.5 ± 22.0 mmHg 和 88.1 ± 13.0 与 89.9 ± 12.6 mmHg,分别),且血压控制不良的比例也较低(男性为 61.1%,女性为 54.8%,P <.001)。除血管紧张素转换酶抑制剂在男性中更为常见外,两种性别使用的抗高血压药物相当。女性对降压药物的依从性更好(女性为 63.6%,男性为 60.1%,P =.015)。总之,与男性相比,埃及高血压女性具有不同的临床特征,其血压控制更好,对降压药物的依从性更高,收缩压和舒张压更低,且所开降压药的分布无明显差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22f7/8678729/32d36f2df31d/JCH-23-1120-g001.jpg

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