Thorn David Roger, Ladewig Hess Ariane Ruth
Praxis Onkologie Basel.
Frauenarztpraxis Basel.
Ther Umsch. 2021 Apr;78(3):136-144. doi: 10.1024/0040-5930/a001250.
Outpatient breast cancer treatment after the hospital: what's next? - Adjuvant medical therapies, management of side effects and common fears, planing and coordination of optimal follow-up care in view of current guidelines Following successful breast cancer surgery patients will generally be facing a certain prolonged period of medical treatment accompanied by several years of follow-up care, usually in the setting of a private practice or outpatient clinic. These medical treatments, which have proven by evidence to substantially reduce the risk of breast cancer recurrence and thereby significantly added to the boost in overall prognosis of this disease, are discussed in the light of current international treatment guidelines in this article. The standard approach to modern medical therapies is outlined on the basis of clinical pathological risk factors and tumor biology for different breast cancer subtypes (e. g. luminal, HER2-positiv, triple negativ / basal-like) accordingly. We hereby focus particularly upon the management of therapy-induced side effects, typical substance-specific toxicities as well as offering remedy to common fears and myths concerning medical breast cancer treatment. Last but not least we describe our perspective of the "ideal outpatient follow-up care", outlining a time-plan, implementing interdisciplinary expertise and stressing the necessity for good teamwork and interaction among all health care specialists involved, to optimise patient comfort and outcome.
接下来该怎么做?——辅助性药物治疗、副作用管理及常见担忧、根据当前指南规划和协调最佳随访护理 乳腺癌手术成功后,患者通常会面临一段较长的治疗期,并伴有数年的随访护理,通常是在私人诊所或门诊环境中。本文根据当前国际治疗指南,讨论了这些已被证明能大幅降低乳腺癌复发风险、从而显著改善该疾病总体预后的治疗方法。基于不同乳腺癌亚型(如管腔型、HER2阳性、三阴性/基底样型)的临床病理风险因素和肿瘤生物学,概述了现代医学治疗的标准方法。在此,我们特别关注治疗引起的副作用管理、典型的药物特异性毒性,以及消除有关乳腺癌治疗的常见担忧和误解。最后但同样重要的是,我们描述了我们对“理想门诊随访护理”的看法,概述了一个时间计划,运用跨学科专业知识,并强调所有参与的医疗保健专家之间良好团队合作和互动的必要性,以优化患者的舒适度和治疗效果。