早产儿视网膜病变模型与 WINROP 模型生长情况的回顾性比较。
Retrospective comparison between growth and retinopathy of prematurity model versus WINROP model.
机构信息
Department of Ophthalmology, Hospital Beatriz Angelo, Loures, Portugal; Neonatal Intensive Care Unit, Hospital São Francisco Xavier - Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal; CEDOC, NOVA Medical School - Universidade Nova de Lisboa, Lisbon, Portugal; Department of Ophthalmology, Hospital da Luz, Lisbon, Portugal.
Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.
出版信息
Can J Ophthalmol. 2022 Feb;57(1):58-64. doi: 10.1016/j.jcjo.2021.02.030. Epub 2021 Mar 23.
OBJECTIVE
To compare the weight and insulin-like growth factor-1 in neonatal retinopathy (WINROP) to the growth and retinopathy of prematurity (G-ROP) model in a Portuguese cohort.
DESIGN
Retrospective case series.
METHODS
Clinical records of consecutive infants who underwent retinopathy of prematurity (ROP) screening from April 2012 to May 2019 were retrospectively reviewed. Both WINROP and G-ROP models were accessed for sensitivity and specificity for type 1 ROP. A separate analysis of both algorithms was performed in infants with gestational age (GA) <30 weeks.
RESULTS
Of the 375 infants included in the study, 313 were eligible for G-ROP analysis and 311 for WINROP. In the G-ROP group, 22 infants developed type 1 ROP (sensitivity 90.91%, 95% confidence interval [CI] 70.84%-98.98%). In the WINROP group, 23 infants needed treatment (sensitivity of 86.96%, 95% CI 66.41%-97.22%). Both models reached 100% sensitivity for type 1 ROP if restricted to GA <30 weeks.
CONCLUSIONS
Both models were easy to use and had similar sensitivities. If restricted to GA <30 weeks, both models detected all type 1 ROP.
目的
比较葡萄牙队列中新生儿视网膜病变（WINROP）与早产儿视网膜病变（ROP）的生长和视网膜病变（G-ROP）模型的体重和胰岛素样生长因子-1（IGF-1）。
设计
回顾性病例系列。
方法
回顾性分析 2012 年 4 月至 2019 年 5 月连续接受早产儿视网膜病变（ROP）筛查的婴儿的临床记录。评估了 WINROP 和 G-ROP 两种模型对 1 型 ROP 的敏感性和特异性。对胎龄（GA）<30 周的婴儿分别对两种算法进行了单独分析。
结果
在纳入研究的 375 名婴儿中，有 313 名婴儿符合 G-ROP 分析标准，有 311 名婴儿符合 WINROP 分析标准。在 G-ROP 组中，有 22 名婴儿发展为 1 型 ROP（敏感性 90.91%，95%置信区间[CI] 70.84%-98.98%）。在 WINROP 组中，有 23 名婴儿需要治疗（敏感性为 86.96%，95%CI 66.41%-97.22%）。如果将 GA<30 周的婴儿限制在内，两种模型对 1 型 ROP 的敏感性均达到 100%。
结论
两种模型都易于使用，且具有相似的敏感性。如果将 GA<30 周的婴儿限制在内，两种模型都可以检测到所有的 1 型 ROP。
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