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腹腔镜妇科手术中肺复张手法与腹腔内注射氢化可的松术后镇痛效果的比较

Postoperative analgesic efficacy of the pulmonary recruitment manoeuvre compared to intraperitoneal hydrocortisone in laparoscopic gynaecological surgeries.

作者信息

Elsakka Ahmed, Elrefai Nisreen, Shehata Jihan, Abdel Mawla Atef Galal

机构信息

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine Cairo University, Egypt.

出版信息

Indian J Anaesth. 2021 Feb;65(2):115-120. doi: 10.4103/ija.IJA_423_20. Epub 2021 Feb 10.

DOI:10.4103/ija.IJA_423_20
PMID:33776085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7983833/
Abstract

BACKGROUND AND AIMS

Laparoscopic surgeries are becoming attractive because of early recovery. Adequate postoperative pain relief may be a major concern. Several methods have been used to relieve laparoscopic postoperative pain.

METHODOLOGY

This prospective, randomised, controlled study was conducted during the period between February and June 2019. Patients were assigned into three groups. Patients in the hydrocortisone group received intraperitoneal 100mg hydrocortisone in 150 ml normal saline together with the routine method to remove carbondioxide (CO2). For patients in the pulmonary recruitment group, CO was exsufflated by pulmonary recruitment manoeuvre together with the routine method to remove CO. In the control group CO was removed by applying gentle abdominal pressure allowing passive exsufflation through the port site.

RESULTS

A total of 57 patients were included in the study. There was no statistically significant difference between the three groups as regards demographic characteristics. There was a statistically significant difference in the 24 h postoperative analgesic consumption (primary outcome) in the hydrocortisone and pulmonary recruitment groups in comparison to the control group:P value <0.001. Also, time to first request for analgesia was significantly longer and the visual analogue scale (VAS) score was significantly lower in the hydrocortisone and pulmonary recruitment groups compared to the control group:P value <0.001.

CONCLUSION

Intraperitoneal hydrocortisone and pulmonary recruitment manoeuvre could both effectively reduce pain after gynaecological laparoscopic surgeries, however, intraperitoneal hydrocortisone might give a longer pain-free time.

摘要

背景与目的

由于恢复快,腹腔镜手术正变得具有吸引力。充分的术后疼痛缓解可能是一个主要关注点。已经使用了几种方法来缓解腹腔镜术后疼痛。

方法

这项前瞻性、随机、对照研究于2019年2月至6月期间进行。患者被分为三组。氢化可的松组的患者在150毫升生理盐水中腹腔内注射100毫克氢化可的松,同时采用常规方法排出二氧化碳(CO₂)。对于肺复张组的患者,通过肺复张手法排出CO₂,同时采用常规方法排出CO₂。在对照组中,通过轻柔的腹部加压排出CO₂,使其通过穿刺孔被动排出。

结果

共有57名患者纳入研究。三组在人口统计学特征方面无统计学显著差异。与对照组相比,氢化可的松组和肺复张组术后24小时镇痛药物消耗量(主要结局)有统计学显著差异:P值<0.001。此外,与对照组相比,氢化可的松组和肺复张组首次要求镇痛的时间显著更长,视觉模拟评分(VAS)显著更低:P值<0.001。

结论

腹腔内注射氢化可的松和肺复张手法均可有效减轻妇科腹腔镜手术后的疼痛,然而,腹腔内注射氢化可的松可能会带来更长的无痛时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347f/7983833/8bc5b39d750f/IJA-65-115-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347f/7983833/9f98333150ef/IJA-65-115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347f/7983833/ff5ac3c0cb84/IJA-65-115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347f/7983833/8bc5b39d750f/IJA-65-115-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347f/7983833/9f98333150ef/IJA-65-115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347f/7983833/ff5ac3c0cb84/IJA-65-115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347f/7983833/8bc5b39d750f/IJA-65-115-g003.jpg

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