与使用醋酸珠氯噻醇注射液相关的抗精神病药恶性综合征
Neuroleptic malignant syndrome associated with the use of injection zuclopenthixol acetate.
作者信息
Shouan Anish, Sinha Ankit Kumar, Grover Sandeep
机构信息
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Ind Psychiatry J. 2020 Jan-Jun;29(1):162-164. doi: 10.4103/ipj.ipj_54_19. Epub 2020 Nov 7.
Abstract
Zuclopenthixol is available in two parenteral formulation,i.e., in the form of acetate and decanoate. It has high affinity for dopamine D1 and D2 receptors. There is limited literature of association of neuroleptic malignant syndrome with the use of zuclopenthixol monotherapy. These case reports have mostly implicated zuclopenthixol decanoate, and also zuclopenthixol acetate. In this report, we present a case of neuroleptic malignant syndrome associated with use of zuclopenthixol acetate.
摘要
珠氯噻醇有两种注射用剂型，即醋酸盐和癸酸盐。它对多巴胺D1和D2受体具有高亲和力。关于使用珠氯噻醇单一疗法与神经阻滞剂恶性综合征关联的文献有限。这些病例报告大多涉及癸酸珠氯噻醇，也有醋酸珠氯噻醇。在本报告中，我们呈现一例与使用醋酸珠氯噻醇相关的神经阻滞剂恶性综合征病例。
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