Enatescu Virgil Radu, Cozma Dragos, Tint Diana, Enatescu Ileana, Simu Mihaela, Giurgi-Oncu Catalina, Lazar Mihai Andrei, Mornos Cristian
Department of Neuroscience, "Victor Babes" University of Medicine and Pharmacy Timisoara, Timisoara, Romania.
Department of Cardiology 1, "Victor Babes" University of Medicine and Pharmacy Timisoara, Timisoara, Romania.
Neuropsychiatr Dis Treat. 2021 Mar 18;17:809-820. doi: 10.2147/NDT.S303644. eCollection 2021.
The relationship between personality traits and cardiovascular disease has gathered sustained interest over the last years, type -D personality (TDP) being significantly associated with coronary artery disease (CAD). However, data regarding the connection between the TDP and the severity of CAD disease is scarce. The aim of our study was to assess the relationship between TDP and the complexity of CAD, and to compare it with other sociodemographic and clinical features.
We conducted a cross-sectional case-control clinical-based study on 221 consecutive hospitalized patients with chest pain (60 ± 10.2 years; 131 men), referred for coronary angiography.
TDP was identified in 42 (19%) patients, using the DS 14 scale. Symptomatology profile was evaluated using the SCL-90 scale. Syntax score was greater in the subgroup of patients with TDP in comparison to non-TDP subgroup (26.21±12.03 vs 15.49±8.89, respectively, p<0.001), and most of SCL-90 symptom dimensions have significantly higher levels in the subgroup of TDP with CAD patients (all p < 0.05). Smoking (β=0.132, p=0.037), dyslipidemia (β=0.149, p=0.013), Diabetes Mellitus (β=232, p<0.001), NA dimension of TDP (β=0.255, p<0.001) and SI (β=0.279, p<0.001) dimension of TDP have a significant contribution to the complexity of CAD assessed by Syntax score.
TDP was associated with a more complex CAD assessed by Syntax score, and may represent a dynamic interface between the biological and psychological vulnerabilities and the symptoms of CAD.
在过去几年中,人格特质与心血管疾病之间的关系一直备受关注,D型人格(TDP)与冠状动脉疾病(CAD)显著相关。然而,关于TDP与CAD疾病严重程度之间联系的数据却很稀少。我们研究的目的是评估TDP与CAD复杂性之间的关系,并将其与其他社会人口统计学和临床特征进行比较。
我们对221例因胸痛连续住院的患者(60±10.2岁;131名男性)进行了一项基于临床的横断面病例对照研究,这些患者均接受了冠状动脉造影检查。
使用DS 14量表,在42例(19%)患者中识别出TDP。使用SCL-90量表评估症状特征。与非TDP亚组相比,TDP患者亚组的Syntax评分更高(分别为26.21±12.03和15.49±8.89,p<0.0),并且在患有CAD的TDP患者亚组中,大多数SCL-90症状维度的水平显著更高(所有p<0.05)。吸烟(β=0.132,p=0.037)、血脂异常(β=0.149,p=0.013)、糖尿病(β=232,p<0.001)、TDP的NA维度(β=0.255,p<0.001)和TDP的SI维度(β=0.279,p<0.001)对通过Syntax评分评估的CAD复杂性有显著贡献。
通过Syntax评分评估,TDP与更复杂的CAD相关,并且可能代表生物和心理易损性与CAD症状之间的动态界面。