中年患者的过敏反应。
Anaphylaxis in middle-aged patients.
作者信息
Francuzik Wojciech, Kraft Magdalena, Scherer Hofmeier Kathrin, Ruëff Franziska, Pföhler Claudia, Treudler Regina, Lang Roland, Hawranek Thomas, Wagner Nicola, Worm Margitta
机构信息
Allergy and Immunology, Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin.
Central Emergency Department, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
出版信息
Allergol Select. 2021 Mar 23;5:133-139. doi: 10.5414/ALX02216E. eCollection 2021.
Age is one of the most important factors influencing the course of anaphylaxis: moreover, the frequency of elicitors of anaphylaxis is age-associated. We analyzed 8,465 anaphylactic episodes in adult patients in three age groups with a focus on patients in the middle-age group (35 - 65 years old). Insect venom was the most frequent trigger in this age group (51.2%) followed by drugs (22.8%) and food (17.3%). Severe reactions were observed in 40.1% of middle-aged patients and occurred more frequently in this age group than in patients below 35 years (27.6%) and less frequently than in patients over 65 years (55.6%). The symptoms and comorbidity profile also changed with age, most significantly regarding the increase in rates of concomitant cardiologic diseases and (severe) cardiovascular symptoms.
年龄是影响过敏反应病程的最重要因素之一；此外，过敏反应诱发因素的频率与年龄相关。我们分析了三个年龄组成年患者的8465次过敏发作情况，重点关注中年组（35 - 65岁）患者。昆虫毒液是该年龄组最常见的触发因素（51.2%），其次是药物（22.8%）和食物（17.3%）。40.1%的中年患者出现严重反应，且该年龄组严重反应的发生率高于35岁以下患者（27.6%），低于65岁以上患者（55.6%）。症状和合并症情况也随年龄变化，最显著的是伴随心脏病和（严重）心血管症状的发生率增加。
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