Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco.
Department of Neurology, University of California, San Francisco, San Francisco.
JAMA Neurol. 2021 Jun 1;78(6):657-665. doi: 10.1001/jamaneurol.2021.0399.
The US aging population is rapidly becoming more racially and ethnically diverse. Early diagnosis of dementia is a health care priority.
To examine the associations between race/ethnicity and timeliness of dementia diagnosis and comprehensiveness of diagnostic evaluation.
DESIGN, SETTING, AND PARTICIPANTS: This retrospective cross-sectional study used 2013-2015 California Medicare fee-for-service data to examine the associations of race/ethnicity, individual factors, and contextual factors with the timeliness and comprehensiveness of dementia diagnosis. Data from 10 472 unique beneficiaries were analyzed. The sample was selected on the basis of the following criteria: presence of 1 or more claims; no diagnoses of dementia or mild cognitive impairment in 2013 to 2014; continuous enrollment in Medicare Parts A and B; Asian, Black, Hispanic, or White race/ethnicity; and incident diagnoses of dementia or mild cognitive impairment in January through June 2015. Data analyses were conducted from November 1, 2019, through November 10, 2020.
Timeliness of diagnosis, defined as incident diagnosis of mild cognitive impairment vs dementia, and comprehensiveness of diagnostic evaluation, defined as presence of the following services in claims within 6 months before or after the incident diagnosis date: specialist evaluation, laboratory testing, and neuroimaging studies.
The sample comprised 10 472 unique Medicare beneficiaries with incident diagnoses of dementia or mild cognitive impairment (6504 women [62.1%]; mean [SD] age, 82.9 [8.0] years) and included 993 individuals who identified as Asian (9.5%), 407 as Black (3.9%), 1255 as Hispanic (12.0%), and 7817 as White (74.6%). Compared with White beneficiaries, those who identified as Asian (odds ratio, 0.46; 95% CI, 0.38-0.56), Black (odds ratio, 0.73; 95% CI, 0.56-0.94), or Hispanic (odds ratio, 0.62; 95% CI, 0.52-0.72) were less likely to receive a timely diagnosis. Asian beneficiaries (incidence rate ratio, 0.81; 95% CI, 0.74-0.87) also received fewer diagnostic evaluation elements. These associations remained significant after adjusting for age, sex, comorbidity burden, neighborhood disadvantage, and rurality.
These findings highlight substantial disparities in the timeliness and comprehensiveness of dementia diagnosis. Public health interventions are needed to achieve equitable care for people living with dementia across all racial/ethnic groups.
美国的老年人口正迅速变得更加多样化,包括种族和民族。早期诊断痴呆症是医疗保健的重点。
研究种族/民族与痴呆症诊断及时性和诊断评估全面性之间的关系。
设计、地点和参与者:这项回顾性的横断面研究使用了 2013-2015 年加利福尼亚州医疗保险按服务付费数据,以研究种族/民族、个体因素和环境因素与痴呆症诊断及时性和全面性的关系。分析了 10472 名独特受益人的数据。该样本是根据以下标准选择的:存在 1 项或多项索赔;2013 年至 2014 年无痴呆症或轻度认知障碍诊断;医疗保险 A 部分和 B 部分连续参保;亚洲、黑人、西班牙裔或白人种族/民族;2015 年 1 月至 6 月期间首次诊断为痴呆症或轻度认知障碍。数据分析于 2019 年 11 月 1 日至 2020 年 11 月 10 日进行。
诊断及时性,定义为轻度认知障碍与痴呆症的首次诊断;诊断评估的全面性,定义为在首次诊断日期前或后 6 个月内索赔中存在以下服务:专家评估、实验室检测和神经影像学研究。
该样本包括 10472 名有痴呆症或轻度认知障碍首次诊断的独特医疗保险受益人(6504 名女性[62.1%];平均[标准差]年龄 82.9[8.0]岁),其中 993 人自认为是亚洲人(9.5%),407 人自认为是黑人(3.9%),1255 人自认为是西班牙裔(12.0%),7817 人自认为是白人(74.6%)。与白人受益相比,自认为是亚洲人(优势比,0.46;95%CI,0.38-0.56)、黑人(优势比,0.73;95%CI,0.56-0.94)或西班牙裔(优势比,0.62;95%CI,0.52-0.72)的人不太可能及时得到诊断。亚洲裔受益人的诊断评估要素也较少(发病率比,0.81;95%CI,0.74-0.87)。这些关联在调整年龄、性别、合并症负担、邻里劣势和农村程度后仍然显著。
这些发现突出了痴呆症诊断及时性和全面性方面的巨大差异。需要采取公共卫生干预措施,为所有种族/民族的痴呆症患者提供公平的护理。