García Atienza Eva María, López-Torres Hidalgo Jesús, Minuesa García María, Ruipérez Moreno María, Lucas Galán Francisco Javier, Agudo Mena José Luis
Servicio de Urgencias, Hospital General de Villarrobledo, Servicio de Salud de Castilla-La Mancha, AlbaceteEspaña.
Centro de Salud Zona VIII de Albacete, Servicio de Salud de Castilla-La Mancha, España.
Aten Primaria. 2021 May;53(5):102041. doi: 10.1016/j.aprim.2021.102041. Epub 2021 Mar 26.
To describe the health-related quality of life (HRQoL) in benzodiazepine users and to verify whether there is an association with the characteristics of the treatment, its effectiveness, and the sociodemographic variables.
Descriptive cross-sectional study.
Family medicine consultations.
Four hundred and fifty 2patients over 18 years of age consuming benzodiazepines or similar drugs.
HRQoL was assessed using the EuroQol5-D questionnaire. Other variables: symptoms of anxiety or insomnia, sociodemographic variables and characteristics of the treatment.
The mean score in health status was 62.80 (95% CI: 60.69-64.86), lower in people without studies (59.27±21.97 SD; P=.004) and lower social category (60.02±21.27 SD; P<.001). Regarding the social rate (EQ index), a mean score of 0.6025 (95% CI: 0.5659-0.6391) was obtained, higher in people with higher education (0.6577±0.3574 SD; P=.001), plus social category (0.7286±0.3381 SD; P<.001) and age less than 65 years (0.6603±0.3426 SD; P<.001). The variables that were associated with the value of the EQ index by means of multiple regression were absence of anxiety/insomnia, belonging to higher social classes, age less than 65 years and less consumption of anxiolytics/hypnotics.
Patients who use benzodiazepines show, despite treatment, a moderate HRQL, lower than that obtained in the general population or in primary care patients. The situation is more favorable in the youngest, in those who do not present anxiety/insomnia, in those belonging to higher social classes and when the consumption of drugs is lower.
描述苯二氮䓬类药物使用者的健康相关生活质量(HRQoL),并验证其与治疗特征、疗效以及社会人口统计学变量之间是否存在关联。
描述性横断面研究。
家庭医学咨询门诊。
450名18岁以上服用苯二氮䓬类药物或类似药物的患者。
使用欧洲五维健康量表(EuroQol5-D)问卷评估HRQoL。其他变量:焦虑或失眠症状、社会人口统计学变量以及治疗特征。
健康状况的平均得分为62.80(95%置信区间:60.69 - 64.86),未受过教育者得分较低(59.27±21.97标准差;P = 0.004),社会阶层较低者得分也较低(60.02±21.27标准差;P < 0.001)。关于社会比率(EQ指数),平均得分为0.6025(95%置信区间:0.5659 - 0.6391),受过高等教育者得分较高(0.6577±0.3574标准差;P = 0.001),社会阶层较高者得分较高(0.7286±0.3381标准差;P < 0.001),年龄小于65岁者得分较高(0.6603±0.3426标准差;P < 0.001)。通过多元回归与EQ指数值相关的变量包括无焦虑/失眠、属于较高社会阶层、年龄小于65岁以及抗焦虑药/催眠药消费量较低。
使用苯二氮䓬类药物的患者尽管接受了治疗,但HRQL仍处于中等水平,低于普通人群或初级保健患者。在最年轻的人群、无焦虑/失眠症状者、社会阶层较高者以及药物消费量较低者中,情况更为有利。