Respiratory Rehabilitation of the Institute of Tradate, Istituti Clinici Scientifici Maugeri, IRCCS, Tradate, Italy.
Respiratory Rehabilitation of the Institute of Lumezzane, Istituti Clinici Scientifici Maugeri, IRCCS, Brescia, Italy.
Respiration. 2021;100(5):416-422. doi: 10.1159/000514387. Epub 2021 Mar 30.
In hospitalized patients recovering from the SARS-coronavirus-2 disease 19 (COVID-19), high prevalence of muscle weakness and physical performance impairment has been observed.
The aim of this study was to evaluate the effectiveness of pulmonary rehabilitation in these subjects in a real-life setting.
Retrospective data analysis of patients recovering from COVID-19, including those requiring assisted ventilation or oxygen therapy, consecutively admitted to an in-patient pulmonary rehabilitation program between April 1 and August 15, 2020. Short Physical Performance Battery (SPPB: primary outcome), Barthel Index (BI), and six-min walking distance were assessed as outcome measures.
Data of 140 patients were analyzed. After rehabilitation, patients showed improvements in SPPB {from: (median [IQR]) 0.5 (0-7) to 7 (4-10), p < 0.001} and BI (from 55 [30-90] to 95 [65-100], p < 0.001), as well as in other assessed outcome measures. The proportion of patients unable at admission to stand, rise from a chair and walk was significantly reduced (p < 0.00).
Pulmonary rehabilitation is possible and effective in patients recovering from COVID-19. Our findings may be useful to guide clinicians taking care of patients surviving COVID-19 infection.
在因严重急性呼吸系统综合征冠状病毒 2 型（SARS-CoV-2）疾病（COVID-19）住院治疗后康复的患者中，观察到肌肉无力和身体机能受损的高患病率。
本研究旨在评估在现实环境中对这些患者进行肺康复治疗的效果。
对 2020 年 4 月 1 日至 8 月 15 日连续收治于住院肺康复计划的 COVID-19 康复患者（包括需要辅助通气或氧疗的患者）进行回顾性数据分析。采用短体适能表现测试（SPPB：主要结局）、巴氏指数（BI）和 6 分钟步行距离作为评估指标。
分析了 140 例患者的数据。康复后，患者 SPPB 评分（从：（中位数[IQR]）0.5（0-7）至 7（4-10），p < 0.001）和 BI（从 55 [30-90]至 95 [65-100]，p < 0.001）均有所改善，其他评估指标也有所改善。入院时无法站立、从椅子上站起来和行走的患者比例显著降低（p < 0.00）。
肺康复对 COVID-19 康复患者是可行且有效的。我们的发现可能有助于指导护理 COVID-19 感染幸存者的临床医生。
