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凝血功能障碍与急性呼吸窘迫综合征:电子烟相关肺损伤的双重并发症

Coagulopathy and Acute Respiratory Distress Syndrome: Dual Complications of E-Cigarette-Associated Lung Injury.

作者信息

Kalantary Atefeh, Abdelazeem Basel, Shams Nasheed, Pratiti Rebecca, Al-Sanouri Ibrahim

机构信息

Internal Medicine, McLaren Health Care, Flint/Michigan State University (MSU), Flint, USA.

Internal Medicine, McLaren Health Care, Flint, USA.

出版信息

Cureus. 2021 Feb 24;13(2):e13531. doi: 10.7759/cureus.13531.

Abstract

E-cigarette-associated lung injury (EVALI) is related to the usage of e-cigarettes or a related product (e.g., "vaping" or "dabbing"). It presents mainly with constitutional, respiratory, or gastrointestinal symptoms, and EVALI is currently a diagnosis of exclusion. EVALI patients are more prone to rapid clinical decline requiring close monitoring, with some requiring intensive care unit (ICU) level of care or intubation. Mortality occurs in rare cases. We are presenting an interesting case of a male in his mid-60s who presented to the emergency department with worsening dyspnea and cough for two weeks, preceded by a one-week history of fever, nausea, and diarrhea. He was diagnosed with bilateral pneumonia based on computed tomography (CT) findings. Subsequent CT of the chest showed worsening bilateral diffuse ground-glass opacities (GGOs) correlating with acute respiratory distress syndrome (ARDS). Laboratory workup showed leukocytosis and lactic acidosis. The rest of the laboratory workup was normal. The patient was intubated due to ARDS, developed multiorgan failure, and passed away subsequently.

摘要

电子烟相关肺损伤(EVALI)与电子烟或相关产品(如“吸电子烟”或“滴吸”)的使用有关。其主要表现为全身、呼吸或胃肠道症状,目前EVALI是一种排除性诊断。EVALI患者更容易出现临床快速恶化,需要密切监测,部分患者需要重症监护病房(ICU)级别的护理或插管。罕见情况下会出现死亡。我们现报告一例有趣的病例,一名60多岁男性因呼吸困难和咳嗽加重两周就诊于急诊科,在此之前有一周的发热、恶心和腹泻病史。根据计算机断层扫描(CT)结果,他被诊断为双侧肺炎。随后的胸部CT显示双侧弥漫性磨玻璃影(GGO)加重,与急性呼吸窘迫综合征(ARDS)相关。实验室检查显示白细胞增多和乳酸酸中毒。其余实验室检查结果正常。该患者因ARDS插管,并发多器官功能衰竭,随后死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/032f/7995955/a914bae2a96a/cureus-0013-00000013531-i01.jpg

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