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Remdesivir for the treatment of COVID-19 in pregnancy.瑞德西韦用于治疗妊娠期新型冠状病毒肺炎
J Med Virol. 2021 Jul;93(7):4114-4119. doi: 10.1002/jmv.26986. Epub 2021 Apr 14.
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Remdesivir (Veklury) for COVID-19.用于治疗新冠肺炎的瑞德西韦（Veklury）
Med Lett Drugs Ther. 2020 Nov 30;62(1612):186-188.
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Biomed Pharmacother. 2020 Oct;130:110532. doi: 10.1016/j.biopha.2020.110532. Epub 2020 Jul 22.
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COVID-19 updates: Remdesivir (Veklury) in high-risk outpatients with COVID-19.2019冠状病毒病最新情况：瑞德西韦（Veklury）用于高危2019冠状病毒病门诊患者。
Med Lett Drugs Ther. 2022 Feb 21;64(1644):31-32.
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Remdesivir for patients with COVID-19.瑞德西韦用于治疗新冠肺炎患者。
CMAJ. 2021 Jan 25;193(4):E125. doi: 10.1503/cmaj.202505. Epub 2021 Jan 6.
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Should Remdesivir Be Used for the Treatment of Patients With COVID-19? Rapid, Living Practice Points From the American College of Physicians (Version 1).瑞德西韦是否应用于治疗 COVID-19 患者？美国医师学会的快速实践要点（第 1 版）。
Ann Intern Med. 2021 Feb;174(2):229-236. doi: 10.7326/M20-5831. Epub 2020 Oct 5.
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Remdesivir as a broad-spectrum antiviral drug against COVID-19.瑞德西韦作为一种广谱抗 COVID-19 病毒药物。
Eur Rev Med Pharmacol Sci. 2021 Jan;25(1):541-548. doi: 10.26355/eurrev_202101_24426.
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[Not Available].[无可用内容]。
CMAJ. 2021 Apr 6;193(14):E495-E496. doi: 10.1503/cmaj.202505-f.
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Use of remdesivir for pregnant patients with severe novel coronavirus disease 2019.瑞德西韦用于患有严重2019新型冠状病毒病的孕妇。
Am J Obstet Gynecol. 2020 Nov;223(5):768-770. doi: 10.1016/j.ajog.2020.08.001. Epub 2020 Aug 7.
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Cardiovascular Considerations of Remdesivir and Favipiravir in the Treatment of COVID-19.瑞德西韦和法匹拉韦治疗 COVID-19 的心血管注意事项。
Cardiovasc Hematol Disord Drug Targets. 2021;21(2):88-90. doi: 10.2174/1871529X21666210812103535.

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1
Remdesivir: treatment of COVID-19 in special populations.瑞德西韦：特殊人群中新型冠状病毒肺炎的治疗
Naunyn Schmiedebergs Arch Pharmacol. 2024 Jun;397(6):3829-3855. doi: 10.1007/s00210-023-02927-2. Epub 2024 Jan 5.
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COVID-19 and Pregnancy: An Updated Review about Evidence-Based Therapeutic Strategies.新型冠状病毒肺炎与妊娠：基于证据的治疗策略最新综述
J Pers Med. 2023 Jun 23;13(7):1035. doi: 10.3390/jpm13071035.
3
Is it possible to reduce the rate of vertical transmission and improve perinatal outcomes by inclusion of remdesivir in treatment regimen of pregnant women with COVID-19?在 COVID-19 孕妇的治疗方案中加入瑞德西韦是否可以降低垂直传播率并改善围产期结局？
BMC Pregnancy Childbirth. 2023 Feb 13;23(1):110. doi: 10.1186/s12884-023-05405-y.
4
Developmental toxicity of remdesivir, an anti-COVID-19 drug, is implicated by in vitro assays using morphogenetic embryoid bodies of mouse and human pluripotent stem cells.瑞德西韦（一种抗 COVID-19 药物）的发育毒性通过使用鼠和人多能干细胞的形态发生胚胎体的体外检测被暗示。
Birth Defects Res. 2023 Jan 15;115(2):224-239. doi: 10.1002/bdr2.2111. Epub 2022 Nov 8.
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Biotransformation and transplacental transfer of the anti-viral remdesivir and predominant metabolite, GS-441524 in pregnant rats.在怀孕大鼠中，抗病毒药物瑞德西韦及其主要代谢物 GS-441524 的生物转化和胎盘转移。
EBioMedicine. 2022 Jul;81:104095. doi: 10.1016/j.ebiom.2022.104095. Epub 2022 Jun 4.

本文引用的文献

1
Inclusion of pregnant women in COVID-19 treatment trials: a review and global call to action.将孕妇纳入 COVID-19 治疗试验：综述与全球行动呼吁。
Lancet Glob Health. 2021 Mar;9(3):e366-e371. doi: 10.1016/S2214-109X(20)30484-8. Epub 2020 Dec 16.
2
Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report.地塞米松、瑞德西韦、康复期血浆及俯卧位通气在妊娠合并重症新型冠状病毒肺炎感染治疗中的应用：一例病例报告
Case Rep Womens Health. 2021 Jan;29:e00273. doi: 10.1016/j.crwh.2020.e00273. Epub 2020 Nov 25.
3
Efficacy and safety of remdesivir in hospitalized Covid-19 patients: Systematic review and meta-analysis including network meta-analysis.瑞德西韦治疗住院 COVID-19 患者的疗效和安全性：系统评价和包括网络荟萃分析的荟萃分析。
Rev Med Virol. 2021 Jul;31(4):e2187. doi: 10.1002/rmv.2187. Epub 2020 Oct 31.
4
Severe COVID-19 in Third Trimester Pregnancy: Multidisciplinary Approach.妊娠晚期的重症新型冠状病毒肺炎：多学科诊疗方法
Case Rep Crit Care. 2020 Oct 14;2020:8889487. doi: 10.1155/2020/8889487. eCollection 2020.
5
Compassionate Use of Remdesivir in Pregnant Women With Severe Coronavirus Disease 2019.瑞德西韦在患有严重2019冠状病毒病的孕妇中的同情用药
Clin Infect Dis. 2021 Dec 6;73(11):e3996-e4004. doi: 10.1093/cid/ciaa1466.
6
Remdesivir Treatment for Severe COVID-19 in Third-Trimester Pregnancy: Case Report and Management Discussion.瑞德西韦治疗孕晚期重症新型冠状病毒肺炎：病例报告与处理讨论
Open Forum Infect Dis. 2020 Aug 24;7(9):ofaa345. doi: 10.1093/ofid/ofaa345. eCollection 2020 Sep.
7
Compassionate use of remdesivir for treatment of severe coronavirus disease 2019 in pregnant women at a United States academic center.在美国一家学术中心对瑞德西韦同情用药治疗妊娠合并重症2019冠状病毒病的研究。
Am J Obstet Gynecol MFM. 2020 Aug;2(3):100164. doi: 10.1016/j.ajogmf.2020.100164. Epub 2020 Jun 25.
8
Use of remdesivir for pregnant patients with severe novel coronavirus disease 2019.瑞德西韦用于患有严重2019新型冠状病毒病的孕妇。
Am J Obstet Gynecol. 2020 Nov;223(5):768-770. doi: 10.1016/j.ajog.2020.08.001. Epub 2020 Aug 7.
9
Tocilizumab and Remdesivir in a Pregnant Patient With Coronavirus Disease 2019 (COVID-19).托珠单抗和瑞德西韦联合治疗 COVID-19 孕妇。
Obstet Gynecol. 2020 Nov;136(5):1025-1029. doi: 10.1097/AOG.0000000000004050.
10
Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study.英国确诊感染 SARS-CoV-2 的住院孕妇的特征和结局：全国基于人群的队列研究。
BMJ. 2020 Jun 8;369:m2107. doi: 10.1136/bmj.m2107.

Remdesivir for the treatment of COVID-19 in pregnancy.

作者信息

Lampejo Temi

机构信息

Department of Infection, Imperial College Healthcare NHS Trust, London, UK.

出版信息

J Med Virol. 2021 Jul;93(7):4114-4119. doi: 10.1002/jmv.26986. Epub 2021 Apr 14.

DOI:10.1002/jmv.26986
PMID:33788273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8250519/
Abstract
摘要