Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan;
Anticancer Res. 2021 Mar;41(3):1547-1553. doi: 10.21873/anticanres.14914.
We sought to identify the risk factors of totally implantable central venous access port (TICVAP)-related infections in patients with malignant disease.
Overall, 324 consecutive patients who received a TICVAP at our institution were retrospectively analysed. We further analysed cases of TICVAP-related complications. The risk factors for TICVAP-related infection were investigated using Cox regression hazard models.
With a median TICVAP duration of 268 days (range=1-1,859 days), TICVAP-related complications were observed in 36 cases and infectious complications in late phase were the most common, seen in 19 cases (9.26%). A multivariate analysis showed that patients with head and neck malignancy (p<0.001) and patients who received TICVAP insertion in the upper arm (p<0.001) were independently at a higher risk for TICVAP-related infections.
Patients with head and neck malignancy or TICVAP insertion in the upper arm have potentially increased risk for late-phase TICVAP-related infections.
我们旨在确定恶性肿瘤患者完全植入式中央静脉通路（TICVAP）相关感染的危险因素。
回顾性分析了我院 324 例连续接受 TICVAP 的患者。我们进一步分析了 TICVAP 相关并发症的病例。使用 Cox 回归风险模型研究 TICVAP 相关感染的危险因素。
TICVAP 中位时间为 268 天（范围=1-1859 天），36 例出现 TICVAP 相关并发症，晚期感染最常见，19 例（9.26%）。多因素分析显示，头颈部恶性肿瘤患者（p<0.001）和 TICVAP 在上臂植入的患者（p<0.001）发生 TICVAP 相关感染的风险更高。
头颈部恶性肿瘤或 TICVAP 在上臂植入的患者发生晚期 TICVAP 相关感染的风险可能增加。
